Cargando…

Coexpression and functional cooperation of CTLA-4 and CD28 on activated T lymphocytes

T cell costimulation by molecules on the antigen presenting cell (APC) is required for optimal T cell proliferation. The B7 molecule on APC binds the T lymphocyte receptor CD28, triggering increased interleukin 2 (IL-2) production and subsequent T cell proliferation. CTLA-4 is a predicted T cell mem...

Descripción completa

Detalles Bibliográficos
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 1992
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2119471/ https://www.ncbi.nlm.nih.gov/pubmed/1334116

Ejemplares similares

Cytotoxic T Lymphocyte Antigen 4 (CTLA4) Blockade Accelerates the Acute Rejection of Cardiac Allografts in CD28-deficient Mice: CTLA4 Can Function Independently of CD28
por: Lin, Hua, et al.
Publicado: (1998)

CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation
Publicado: (1995)

Do Human iPSC-Derived Cardiomyocytes Cultured on PLA Scaffolds Induce Expression of CD28/CTLA-4 by T Lymphocytes?
por: Sergeevichev, David, et al.
Publicado: (2022)

CTLA4-CD28 chimera gene modification of T cells enhances the therapeutic efficacy of donor lymphocyte infusion for hematological malignancy
por: Park, Hyung Bae, et al.
Publicado: (2017)

CD28-Dependent CTLA-4 Expression Fine-Tunes the Activation of Human Th17 Cells
por: Krummey, Scott M., et al.
Publicado: (2020)

Expression patterns of CD28 and CTLA‐4 in early, chronic, and untreated rheumatoid arthritis
por: García‐Chagollán, Mariel, et al.
Publicado: (2020)

Modulation of Regulatory T Cells Activity by Distinct CD80 and CD86 Interactions With CD28/CTLA-4 in Chagas Cardiomyopathy
por: Pinto, Bruna F., et al.
Publicado: (2022)

Alterations of the expression of T-cell-related costimulatory CD28 and downregulatory CD152 (CTLA-4) molecules in patients with B-cell chronic lymphocytic leukaemia
por: Frydecka, I, et al.
Publicado: (2004)

Identification of residues in the V domain of CD80 (B7-1) implicated in functional interactions with CD28 and CTLA4
Publicado: (1995)

Polymorphisms in the CD28/CTLA4/ICOS genes: role in malignant melanoma susceptibility and prognosis?
por: Bouwhuis, Marna G., et al.
Publicado: (2009)

Personalized treatment of Sézary syndrome by targeting a novel CTLA4:CD28 fusion
por: Sekulic, Aleksandar, et al.
Publicado: (2015)

Differences in allergen-induced T cell activation between allergic asthma and rhinitis: Role of CD28, ICOS and CTLA-4
por: Botturi, Karine, et al.
Publicado: (2011)

Co-Stimulatory Blockade of the CD28/CD80-86/CTLA-4 Balance in Transplantation: Impact on Memory T Cells?
por: Ville, Simon, et al.
Publicado: (2015)

Differential regulation of motility and immune synapses by CD28/ CTLA-4 costimulation in effector and regulatory T cells
por: Dilek, Nahzli, et al.
Publicado: (2012)

Chemokine receptors expression on peripheral CD4-lymphocytes in rheumatoid arthritis: Coexpression of CCR7 and CD95 is associated with disease activity
por: Aldahlawi, Alia M., et al.
Publicado: (2015)

Molecular and Functional Analyses of the Primordial Costimulatory Molecule CD80/86 and Its Receptors CD28 and CD152 (CTLA-4) in a Teleost Fish
por: Lu, Tao-Zhen, et al.
Publicado: (2022)

CD28/CTLA-4/ICOS haplotypes confers susceptibility to Graves’ disease and modulates clinical phenotype of disease
por: Pawlak-Adamska, Edyta, et al.
Publicado: (2016)

Chimeric CTLA4-CD28-CD3z T Cells Potentiate Antitumor Activity Against CD80/CD86–Positive B Cell Malignancies
por: Lin, Shouheng, et al.
Publicado: (2021)

CD80 (B7-1) Binds Both CD28 and CTLA-4 with a Low Affinity and Very Fast Kinetics
por: van der Merwe, P. Anton, et al.
Publicado: (1997)

Tumor-Targeted Human T Cells Expressing CD28-Based Chimeric Antigen Receptors Circumvent CTLA-4 Inhibition
por: Condomines, Maud, et al.
Publicado: (2015)

The Association Between CTLA-4, CD80/86, and CD28 Gene Polymorphisms and Rheumatoid Arthritis: An Original Study and Meta-Analysis
por: Liu, Weixi, et al.
Publicado: (2021)

Targeting CD28, CTLA-4 and PD-L1 Costimulation Differentially Controls Immune Synapses and Function of Human Regulatory and Conventional T-Cells
por: Dilek, Nahzli, et al.
Publicado: (2013)

Erratum to: CD28/CTLA-4/ICOS haplotypes confers susceptibility to Graves’ disease and modulates clinical phenotype of disease
por: Pawlak-Adamska, Edyta, et al.
Publicado: (2017)

CTLA-4-Tg/CD-28-KO Mice Exhibit Reduced T Cell Proliferation in vivo Compared to CD-28-KO Mice in a Graft-versus-host Disease Model
por: Yoo, Jong-Sun, et al.
Publicado: (2012)

Role of CTLA4 in the Proliferation and Survival of Chronic Lymphocytic Leukemia
por: Mittal, Amit K., et al.
Publicado: (2013)

Differential trafficking of ligands trogocytosed via CD28 versus CTLA4 promotes collective cellular control of co-stimulation
por: Zenke, Simon, et al.
Publicado: (2022)

Absence of CD28-CTLA4-PD-L1 Costimulatory Molecules Reduces Herpes Simplex Virus 1 Reactivation
por: Matundan, Harry H., et al.
Publicado: (2021)

CTLA-4 blockade boosts the expansion of tumor-reactive CD8(+) tumor-infiltrating lymphocytes in ovarian cancer
por: Friese, Christina, et al.
Publicado: (2020)

CD8(+) T Lymphocyte Coexpression Genes Correlate with Immune Microenvironment and Overall Survival in Breast Cancer
por: Jiang, Jialing, et al.
Publicado: (2021)

CD86 Is a Selective CD28 Ligand Supporting FoxP3+ Regulatory T Cell Homeostasis in the Presence of High Levels of CTLA-4
por: Halliday, Neil, et al.
Publicado: (2020)

Cytotoxic T Lymphocyte–associated Antigen 4 (CTLA-4) Can Regulate Dendritic Cell–induced Activation and Cytotoxicity of CD8(+) T Cells Independently of CD4(+)T Cell Help
por: McCoy, Kathy D., et al.
Publicado: (1999)

Mice transgenic for human CTLA4-CD28 fusion gene show proliferation and transformation of ATLL-like and AITL-like T cells
por: Lee, Gyu Jin, et al.
Publicado: (2022)

Cooperative Roles of CTLA-4 and Regulatory T Cells in Tolerance to an Islet Cell Antigen
por: Eggena, Mark P., et al.
Publicado: (2004)

CD152 (CTLA-4) Determines CD4 T Cell Migration In Vitro and In Vivo
por: Knieke, Karin, et al.
Publicado: (2009)

A major population of mucosal memory CD4(+) T cells, coexpressing IL-18Rα and DR3, display innate lymphocyte functionality
por: Holmkvist, P, et al.
Publicado: (2015)

Minimal hepatic encephalopathy is associated with expansion and activation of CD(4+)CD28(−), Th22 and Tfh and B lymphocytes
por: Mangas-Losada, Alba, et al.
Publicado: (2017)

CTLA-4-mediated posttranslational modifications direct cytotoxic T-lymphocyte differentiation
por: Lingel, Holger, et al.
Publicado: (2017)

Migration of Th1 Lymphocytes Is Regulated by CD152 (CTLA-4)-Mediated Signaling via PI3 Kinase-Dependent Akt Activation
por: Knieke, Karin, et al.
Publicado: (2012)

Distinct roles for CD28 and cytotoxic T lymphocyte-associated molecule- 4 receptors during T cell activation?
Publicado: (1995)

CTLA-4 ligation blocks CD28-dependent T cell activation [published erratum appears in J Exp Med 1996 Jul 1;184(1):301]
Publicado: (1996)

Cannot write session to /tmp/vufind_sessions/sess_nolsigvgcehol2a2aeh4p0ctop