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Coexpression and functional cooperation of CTLA-4 and CD28 on activated T lymphocytes

T cell costimulation by molecules on the antigen presenting cell (APC) is required for optimal T cell proliferation. The B7 molecule on APC binds the T lymphocyte receptor CD28, triggering increased interleukin 2 (IL-2) production and subsequent T cell proliferation. CTLA-4 is a predicted T cell mem...

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Detalles Bibliográficos
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 1992
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2119471/ https://www.ncbi.nlm.nih.gov/pubmed/1334116

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