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Discrete nascent chain lengths are required for the insertion of presecretory proteins into microsomal membranes
Ribosomes synthesizing nascent secretory proteins are targeted to the membrane by the signal recognition particle (SRP), a small ribonucleoprotein that binds to the signal peptide as it emerges from the ribosome. SRP arrests further elongation, causing ribosomes to stack behind the arrested ribosome...
Formato: | Texto |
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Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1993
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2119713/ https://www.ncbi.nlm.nih.gov/pubmed/8389768 |