Cargando…

GTPase domain of the 54-kD subunit of the mammalian signal recognition particle is required for protein translocation but not for signal sequence binding

The 54-kD subunit of the signal recognition particle (SRP54) binds to signal sequences of nascent secretory and transmembrane proteins. SRP54 consists of two separable domains, a 33-kD amino-terminal domain that contains a GTP-binding site (SRP54G) and a 22-kD carboxy-terminal domain (SRP54M) contai...

Descripción completa

Detalles Bibliográficos
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 1993
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2119734/ https://www.ncbi.nlm.nih.gov/pubmed/8382204

Ejemplares similares

The signal sequence interacts with the methionine-rich domain of the 54- kD protein of signal recognition particle
Publicado: (1991)

The 54-kD protein of signal recognition particle contains a methionine- rich RNA binding domain
Publicado: (1990)

Saccharomyces cerevisiae and Schizosaccharomyces pombe contain a homologue to the 54-kD subunit of the signal recognition particle that in S. cerevisiae is essential for growth
Publicado: (1989)

The Ribosome Regulates the Gtpase of the β-Subunit of the Signal Recognition Particle Receptor
por: Bacher, Gerald, et al.
Publicado: (1999)

Assembly of the 68- and 72-kD proteins of signal recognition particle with 7S RNA
Publicado: (1993)

The beta subunit of the signal recognition particle receptor is a transmembrane GTPase that anchors the alpha subunit, a peripheral membrane GTPase, to the endoplasmic reticulum membrane
Publicado: (1995)

Protein translocation across the ER requires a functional GTP binding site in the alpha subunit of the signal recognition particle receptor
Publicado: (1992)

Human autoantibodies against the 54 kDa protein of the signal recognition particle block function at multiple stages
por: Römisch, Karin, et al.
Publicado: (2006)

RNA gymnastics in mammalian signal recognition particle assembly
por: Wild, Klemens, et al.
Publicado: (2015)

Recognition of a 170 kD protein in mammalian Golgi complexes by an antibody against malarial intraerythrocytic lamellae
por: Li, Wenlu, et al.
Publicado: (1995)

Molecular mechanism of cargo recognition and handover by the mammalian signal recognition particle
por: Jomaa, Ahmad, et al.
Publicado: (2021)

YGL138(t), encoding a putative signal recognition particle 54 kDa protein, is involved in chloroplast development of rice
por: Zhang, Fantao, et al.
Publicado: (2013)

A Functional GTPase Domain, but not its Transmembrane Domain, is Required for Function of the SRP Receptor β-subunit
por: Ogg, Stephen C., et al.
Publicado: (1998)

The signal sequence receptor, unlike the signal recognition particle receptor, is not essential for protein translocation
Publicado: (1992)

Zinc finger domain of Ro60kD autoantigen is essential for binding of Ro52kD and autoantibodies
por: Routsias, JG, et al.
Publicado: (2003)

Conformational changes in the GTPase modules of the signal reception particle and its receptor drive initiation of protein translocation
por: Shan, Shu-ou, et al.
Publicado: (2007)

Signal recognition particle causes a transient arrest in the biosynthesis of prepromelittin and mediates its translocation across mammalian endoplasmic reticulum
Publicado: (1987)

180-kD ribosome receptor is essential for both ribosome binding and protein translocation
Publicado: (1993)

Noncanonical Functions and Cellular Dynamics of the Mammalian Signal Recognition Particle Components
por: Faoro, Camilla, et al.
Publicado: (2021)

ER translocation intermediates are adjacent to a nonglycosylated 34-kD integral membrane protein
Publicado: (1991)

Characterization of A 54-kD protein of the inner nuclear membrane: evidence for cell cycle-dependent interaction with the nuclear lamina
Publicado: (1991)

The GTPase switch in ribosomal translocation
por: Moore, Pete
Publicado: (2005)

Intrapolypeptide Interactions between the GTPase Effector Domain (GED) and the GTPase Domain Form the Bundle Signaling Element in Dynamin Dimers
por: Srinivasan, Saipraveen, et al.
Publicado: (2014)

Protein translocation across the endoplasmic reticulum. II. Isolation and characterization of the signal recognition particle receptor
Publicado: (1982)

Recognition of a signal peptide by the signal recognition particle
por: Janda, Claudia Y., et al.
Publicado: (2010)

Immune Recognition of the 60kD Heat Shock Protein: Implications for Subsequent Fertility
por: Witkin, Steven S., et al.
Publicado: (1996)

Restriction of 480/270-kD Ankyrin (G) to Axon Proximal Segments Requires Multiple Ankyrin (G)-specific Domains
por: Zhang, Xu, et al.
Publicado: (1998)

GTP hydrolysis by complexes of the signal recognition particle and the signal recognition particle receptor
Publicado: (1993)

Structures of SRP54 and SRP19, the Two Proteins that Organize the Ribonucleic Core of the Signal Recognition Particle from Pyrococcus furiosus
por: Egea, Pascal F., et al.
Publicado: (2008)

Uroplakin I: a 27-kD protein associated with the asymmetric unit membrane of mammalian urothelium
Publicado: (1990)

The mammalian 43-kD acetylcholine receptor-associated protein (RAPsyn) is expressed in some nonmuscle cells
Publicado: (1989)

Structural and immunological characterization of the myosin-like 110-kD subunit of the intestinal microvillar 110K-calmodulin complex: evidence for discrete myosin head and calmodulin-binding domains
Publicado: (1988)

Clustering of the acetylcholine receptor by the 43-kD protein: involvement of the zinc finger domain
Publicado: (1993)

The 43-kD polypeptide of heart gap junctions: immunolocalization, topology, and functional domains
Publicado: (1989)

Depletion of signal recognition particle 72kDa increases radiosensitivity
por: Prevo, Remko, et al.
Publicado: (2017)

The Gut Microbiome of 54 Mammalian Species
por: de Jonge, Nadieh, et al.
Publicado: (2022)

Translocation in yeast and mammalian cells: not all signal sequences are functionally equivalent
Publicado: (1987)

Comparative characterization of the 21-kD and 26-kD gap junction proteins in murine liver and cultured hepatocytes
Publicado: (1989)

Identification of a 52-kD calmodulin-binding protein associated with the mitotic spindle apparatus in mammalian cells
Publicado: (1986)

Protein translocation across the endoplasmic reticulum. I. Detection in the microsomal membrane of a receptor for the signal recognition particle
Publicado: (1982)

Cannot write session to /tmp/vufind_sessions/sess_dm2uuscla46vbtb3jcpodarh7u