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Retinoic acid disrupts the Golgi apparatus and increases the cytosolic routing of specific protein toxins
All-trans retinoic acid can specifically increase receptor mediated intoxication of ricin A chain immunotoxins more than 10,000 times, whereas fluid phase endocytosis of ricin A chain alone or ricin A chain immunotoxins was not influenced by retinoic acid. The immunotoxin activation by retinoic acid...
Formato: | Texto |
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Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1994
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2120076/ https://www.ncbi.nlm.nih.gov/pubmed/8188744 |
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