Cargando…

Altered localization and cytoplasmic domain-binding properties of tyrosine-phosphorylated beta 1 integrin

We describe a novel approach to study tyrosine-phosphorylated (PY) integrins in cells transformed by virally encoded tyrosine kinases. We have synthesized a peptide (PY beta 1 peptide) that represents a portion of the cytoplasmic domain of the beta 1 integrin subunit and is phosphorylated on the tyr...

Descripción completa

Detalles Bibliográficos
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 1994
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2120155/ https://www.ncbi.nlm.nih.gov/pubmed/7520449

Ejemplares similares

Focal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domains
Publicado: (1995)

Cytoplasmic and transmembrane domains of integrin beta 1 and beta 3 subunits are functionally interchangeable
Publicado: (1991)

Contrasting roles for integrin beta 1 and beta 5 cytoplasmic domains in subcellular localization, cell proliferation, and cell migration
Publicado: (1994)

New insights into the phosphorylation of the threonine motif of the β1 integrin cytoplasmic domain
por: Böttcher, Ralph T, et al.
Publicado: (2022)

Modulation of β1A Integrin Functions by Tyrosine Residues in the β1 Cytoplasmic Domain
por: Sakai, Takao, et al.
Publicado: (1998)

Stimulation of beta1 integrins on fibroblasts induces PDGF independent tyrosine phosphorylation of PDGF beta-receptors
Publicado: (1996)

The cytoplasmic domain of the integrin lymphocyte function-associated antigen 1 beta subunit: sites required for binding to intercellular adhesion molecule 1 and the phorbol ester-stimulated phosphorylation site
Publicado: (1991)

Expression and functional analysis of a cytoplasmic domain variant of the beta 1 integrin subunit
Publicado: (1993)

Beta 2 integrin-dependent protein tyrosine phosphorylation and activation of the FGR protein tyrosine kinase in human neutrophils
Publicado: (1994)

Identification of amino acid sequences in the integrin beta 1 cytoplasmic domain implicated in cytoskeletal association
Publicado: (1992)

Adhesive ligand binding to integrin alpha IIb beta 3 stimulates tyrosine phosphorylation of novel protein substrates before phosphorylation of pp125FAK
Publicado: (1993)

Antibodies to the conserved cytoplasmic domain of the integrin beta 1 subunit react with proteins in vertebrates, invertebrates, and fungi
Publicado: (1988)

Src Kinase Phosphorylates RUNX3 at Tyrosine Residues and Localizes the Protein in the Cytoplasm
por: Goh, Yun-Mi, et al.
Publicado: (2010)

Regulation of alpha 6 beta 1 integrin laminin receptor function by the cytoplasmic domain of the alpha 6 subunit
Publicado: (1993)

Beta 2 integrin-dependent tyrosine phosphorylation of paxillin in human neutrophils treated with tumor necrosis factor
Publicado: (1994)

Integrin Ligation Results in Nephrin Tyrosine Phosphorylation In Vitro
por: Verma, Rakesh, et al.
Publicado: (2016)

Distinct functions of integrin alpha and beta subunit cytoplasmic domains in cell spreading and formation of focal adhesions
Publicado: (1993)

Defective phosphorylation and hyaluronate binding of CD44 with point mutations in the cytoplasmic domain
Publicado: (1995)

Identification of Inhibitors of Integrin Cytoplasmic Domain Interactions With Syk
por: Bakthavatsalam, Deenadayalan, et al.
Publicado: (2021)

Expression and function of chicken integrin beta 1 subunit and its cytoplasmic domain mutants in mouse NIH 3T3 cells
Publicado: (1990)

Integrin beta 3 cytoplasmic tail is necessary and sufficient for regulation of alpha 5 beta 1 phagocytosis by alpha v beta 3 and integrin-associated protein
Publicado: (1995)

Integrin cytoplasmic domains mediate inside-out signal transduction
Publicado: (1994)

Functional role of the cytoplasmic domain of the integrin alpha 5 subunit
Publicado: (1993)

The alpha v beta 6 integrin promotes proliferation of colon carcinoma cells through a unique region of the beta 6 cytoplasmic domain
Publicado: (1994)

The integrin cytoplasmic domain-associated protein ICAP-1 binds and regulates Rho family GTPases during cell spreading
por: Degani, Simona, et al.
Publicado: (2002)

The role of protein tyrosine phosphorylation in integrin-mediated gene induction in monocytes
Publicado: (1994)

ICAP-1, a Novel β(1) Integrin Cytoplasmic Domain–associated Protein, Binds to a Conserved and Functionally Important NPXY Sequence Motif of β(1) Integrin
por: Chang, David D., et al.
Publicado: (1997)

The membrane-distal regions of integrin α cytoplasmic domains contribute differently to integrin inside-out activation
por: Thinn, Aye Myat Myat, et al.
Publicado: (2018)

Spermidine/spermine N (1)-acetyltransferase specifically binds to the integrin α9 subunit cytoplasmic domain and enhances cell migration
por: Chen, Chun, et al.
Publicado: (2004)

T cell receptor- and beta 1 integrin-mediated signals synergize to induce tyrosine phosphorylation of focal adhesion kinase (pp125FAK) in human T cells
Publicado: (1995)

Tyrosine Phosphorylation of Botulinum Neurotoxin Protease Domains
por: Toth, Stephen, et al.
Publicado: (2012)

Integrin beta 4 (ITGB4) and its tyrosine-1510 phosphorylation promote pancreatic tumorigenesis and regulate the MEK1-ERK1/2 signaling pathway
por: Meng, Xiangli, et al.
Publicado: (2020)

The Nonreceptor Protein Tyrosine Phosphatase PTP1B Binds to the Cytoplasmic Domain of N-Cadherin and Regulates the Cadherin–Actin Linkage
por: Balsamo, Janne, et al.
Publicado: (1998)

Interchangeable alpha chain cytoplasmic domains play a positive role in control of cell adhesion mediated by VLA-4, a beta 1 integrin
Publicado: (1993)

Beta 3-endonexin, a novel polypeptide that interacts specifically with the cytoplasmic tail of the integrin beta 3 subunit
Publicado: (1995)

A novel integrin specificity exemplified by binding of the alpha v beta 5 integrin to the basic domain of the HIV Tat protein and vitronectin
Publicado: (1993)

Integrin-dependent phosphorylation and activation of the protein tyrosine kinase pp125FAK in platelets
Publicado: (1992)

Integrin β(3) Crosstalk with VEGFR Accommodating Tyrosine Phosphorylation as a Regulatory Switch
por: West, Xiaoxia Z., et al.
Publicado: (2012)

Implications of the differing roles of the β1 and β3 transmembrane and cytoplasmic domains for integrin function
por: Lu, Zhenwei, et al.
Publicado: (2016)

GSK‐3β Phosphorylation of Cytoplasmic Dynein Reduces Ndel1 Binding to Intermediate Chains and Alters Dynein Motility
por: Gao, Feng J., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_79q73c5gp0oq9nth231bastajr