Scatter factor and the c-met receptor: a paradigm for mesenchymal/epithelial interaction

Epithelia and mesenchyme interact during various physiologic and pathologic processes. Scatter factor is a mesenchyme-derived cytokine that stimulates motility, proliferation, and morphogenesis of epithelia. Recent studies suggest that scatter factor and its receptor (c-met) mediate mesenchyme/epith...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1994
Materias:
Mini-Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2120304/
https://www.ncbi.nlm.nih.gov/pubmed/7806559
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collection PubMed
description Epithelia and mesenchyme interact during various physiologic and pathologic processes. Scatter factor is a mesenchyme-derived cytokine that stimulates motility, proliferation, and morphogenesis of epithelia. Recent studies suggest that scatter factor and its receptor (c-met) mediate mesenchyme/epithelia signalling and even interconversion. In this mini-review, we will discuss how scatter factor and c-met may mediate interactions between mesenchyme and epithelia during embryogenesis, organ repair, and neoplasia.
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spelling pubmed-21203042008-05-01 Scatter factor and the c-met receptor: a paradigm for mesenchymal/epithelial interaction J Cell Biol Mini-Reviews Epithelia and mesenchyme interact during various physiologic and pathologic processes. Scatter factor is a mesenchyme-derived cytokine that stimulates motility, proliferation, and morphogenesis of epithelia. Recent studies suggest that scatter factor and its receptor (c-met) mediate mesenchyme/epithelia signalling and even interconversion. In this mini-review, we will discuss how scatter factor and c-met may mediate interactions between mesenchyme and epithelia during embryogenesis, organ repair, and neoplasia. The Rockefeller University Press 1994-12-02 /pmc/articles/PMC2120304/ /pubmed/7806559 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Mini-Reviews
Scatter factor and the c-met receptor: a paradigm for mesenchymal/epithelial interaction
title Scatter factor and the c-met receptor: a paradigm for mesenchymal/epithelial interaction
title_full Scatter factor and the c-met receptor: a paradigm for mesenchymal/epithelial interaction
title_fullStr Scatter factor and the c-met receptor: a paradigm for mesenchymal/epithelial interaction
title_full_unstemmed Scatter factor and the c-met receptor: a paradigm for mesenchymal/epithelial interaction
title_short Scatter factor and the c-met receptor: a paradigm for mesenchymal/epithelial interaction
title_sort scatter factor and the c-met receptor: a paradigm for mesenchymal/epithelial interaction
topic Mini-Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2120304/
https://www.ncbi.nlm.nih.gov/pubmed/7806559

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