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Stage- and ribosome-specific alterations in nascent chain-Sec61p interactions accompany translocation across the ER membrane
Near-neighbor interactions between translocating nascent chains and Sec61p were investigated by chemical cross-linking. At stages of translocation before signal sequence cleavage, nascent chains could be cross-linked to Sec61p at high (60-80%) efficiencies. Cross-linking occurred through the signal...
Formato: | Texto |
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Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1995
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2120490/ https://www.ncbi.nlm.nih.gov/pubmed/7744967 |
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