A v-SNARE implicated in intra-Golgi transport

We report the identification of a putative v-SNARE (GOS-28), localized primarily to transport vesicles at the terminal rims of Golgi stacks. In vitro, GOS-28, A Golgi SNARE of 28 kD, is efficiently packaged into Golgi-derived vesicles, which are most likely COPI coated. Antibodies directed against G...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1996
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2120813/
https://www.ncbi.nlm.nih.gov/pubmed/8636227
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collection PubMed
description We report the identification of a putative v-SNARE (GOS-28), localized primarily to transport vesicles at the terminal rims of Golgi stacks. In vitro, GOS-28, A Golgi SNARE of 28 kD, is efficiently packaged into Golgi-derived vesicles, which are most likely COPI coated. Antibodies directed against GOS-28 block its ability to bind alpha-SNAP, partially inhibit transport from the cis to the medial cisternae, and do not inhibit budding of COP-coated vesicles, but do accumulate docked uncoated vesicles.
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spelling pubmed-21208132008-05-01 A v-SNARE implicated in intra-Golgi transport J Cell Biol Articles We report the identification of a putative v-SNARE (GOS-28), localized primarily to transport vesicles at the terminal rims of Golgi stacks. In vitro, GOS-28, A Golgi SNARE of 28 kD, is efficiently packaged into Golgi-derived vesicles, which are most likely COPI coated. Antibodies directed against GOS-28 block its ability to bind alpha-SNAP, partially inhibit transport from the cis to the medial cisternae, and do not inhibit budding of COP-coated vesicles, but do accumulate docked uncoated vesicles. The Rockefeller University Press 1996-05-01 /pmc/articles/PMC2120813/ /pubmed/8636227 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
A v-SNARE implicated in intra-Golgi transport
title A v-SNARE implicated in intra-Golgi transport
title_full A v-SNARE implicated in intra-Golgi transport
title_fullStr A v-SNARE implicated in intra-Golgi transport
title_full_unstemmed A v-SNARE implicated in intra-Golgi transport
title_short A v-SNARE implicated in intra-Golgi transport
title_sort v-snare implicated in intra-golgi transport
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2120813/
https://www.ncbi.nlm.nih.gov/pubmed/8636227

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