Bax does not have to adopt its final form to drive T cell death

The introduction of antigen into animals causes antigen-specific T cells to divide and then die. Activated T cell death requires either of the death effector molecules, Bak or Bax. When T cells die, Bak and Bax change their conformations, a phenomenon that is thought to be required for Bak or Bax to...

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Detalles Bibliográficos
Autores principales: Zhu, Yanan, Liu, Xinqi, Hildeman, David, Peyerl, Fred W., White, Janice, Kushnir, Elenora, Kappler, John, Marrack, Philippa
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Brief Definitive Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2121198/
https://www.ncbi.nlm.nih.gov/pubmed/16651384
http://dx.doi.org/10.1084/jem.20051736

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