NOD.c3c4 congenic mice develop autoimmune biliary disease that serologically and pathogenetically models human primary biliary cirrhosis

Primary biliary cirrhosis (PBC) is an autoimmune disease with a strong genetic component characterized by biliary ductular inflammation with eventual liver cirrhosis. The serologic hallmark of PBC is antimitochondrial antibodies that react with the pyruvate dehydrogenase complex, targeting the inner...

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Detalles Bibliográficos
Autores principales: Irie, Junichiro, Wu, Yuehong, Wicker, Linda S., Rainbow, Daniel, Nalesnik, Michael A., Hirsch, Raphael, Peterson, Laurence B., Leung, Patrick S.C., Cheng, Chunmei, Mackay, Ian R., Gershwin, M. Eric, Ridgway, William M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2121204/
https://www.ncbi.nlm.nih.gov/pubmed/16636131
http://dx.doi.org/10.1084/jem.20051911

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