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RARγ is critical for maintaining a balance between hematopoietic stem cell self-renewal and differentiation
Hematopoietic stem cells (HSCs) sustain lifelong production of all blood cell types through finely balanced divisions leading to self-renewal and differentiation. Although several genes influencing HSC self-renewal have been identified, to date no gene has been described that, when activated, enhanc...
Autores principales: | Purton, Louise E., Dworkin, Sebastian, Olsen, Gemma Haines, Walkley, Carl R., Fabb, Stewart A., Collins, Steven J., Chambon, Pierre |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2121209/ https://www.ncbi.nlm.nih.gov/pubmed/16682494 http://dx.doi.org/10.1084/jem.20052105 |
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