Cargando…

A common polymorphism in the oxygen-dependent degradation (ODD) domain of hypoxia inducible factor-1α (HIF-1α) does not impair Pro-564 hydroxylation

BACKGROUND: The hypoxia-inducible factor (HIF) transcription complex, which is activated by low oxygen tension, controls a diverse range of cellular processes including angiogenesis and erythropoiesis. Under normoxic conditions, the α subunit of HIF is rapidly degraded in a manner dependent on hydro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Percy, Melanie J, Mooney, Sharon M, McMullin, Mary Frances, Flores, Adrian, Lappin, Terence RJ, Lee, Frank S
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2003
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC212228/ https://www.ncbi.nlm.nih.gov/pubmed/14521712 http://dx.doi.org/10.1186/1476-4598-2-31

Ejemplares similares

Proline-Hydroxylated Hypoxia-Inducible Factor 1α (HIF-1α) Upregulation in Human Tumours
por: Snell, Cameron E., et al.
Publicado: (2014)

Cardiopulmonary function in two human disorders of the hypoxia-inducible factor (HIF) pathway: von Hippel-Lindau disease and HIF-2α gain-of-function mutation
por: Formenti, Federico, et al.
Publicado: (2011)

EGLN1 prolyl hydroxylation of hypoxia-induced transcription factor HIF1α is repressed by SET7-catalyzed lysine methylation
por: Tang, Jinhua, et al.
Publicado: (2022)

HIF1α stabilization in hypoxia is not oxidant-initiated
por: Kumar, Amit, et al.
Publicado: (2021)

SENP1 promotes hypoxia-induced cancer stemness by HIF-1α deSUMOylation and SENP1/HIF-1α positive feedback loop
por: Cui, Chun-Ping, et al.
Publicado: (2017)

HIF1α-dependent hypoxia response in myeloid cells requires IRE1α
por: Mawambo, Gaëlle, et al.
Publicado: (2023)

Characterization and functional analysis of hypoxia-inducible factor HIF1α and its inhibitor HIF1αn in tilapia
por: Li, Hong Lian, et al.
Publicado: (2017)

Association of Age with the Expression of Hypoxia-Inducible Factors HIF-1α, HIF-2α, HIF-3α and VEGF in Lung and Heart of Tibetan Sheep
por: He, Yanyu, et al.
Publicado: (2019)

Impact of the Hypoxia-Inducible Factor-1 α (HIF1A) Pro582Ser Polymorphism on Diabetes Nephropathy
por: Gu, Harvest F., et al.
Publicado: (2013)

HIF-1α, HIF-2α, and ProExC: diagnostic or prognostic relevance in conjunctival intraepithelial neoplasia?
por: Nuessle, Simone, et al.
Publicado: (2020)

HIF-2α, but not HIF-1α, mediates hypoxia-induced up-regulation of Flt-1 gene expression in placental trophoblasts
por: Sasagawa, Tadashi, et al.
Publicado: (2018)

L3MBTL3 is induced by HIF-1α and fine tunes the HIF-1α degradation under hypoxia in vitro
por: Wang, Mengdong, et al.
Publicado: (2023)

VBP1 negatively regulates CHIP and selectively inhibits the activity of hypoxia-inducible factor (HIF)-1α but not HIF-2α
por: Yue, Yiming, et al.
Publicado: (2023)

Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts
por: Mole, David R., et al.
Publicado: (2009)

Dysregulation of hypoxia-inducible factor-1α (Hif1α) expression in the Hmox1-deficient placenta
por: Zhao, Hui, et al.
Publicado: (2020)

Reciprocal relationship between expression of hypoxia inducible factor 1α (HIF-1α) and the pro-apoptotic protein Bid in ex vivo colorectal cancer
por: Seenath, M M, et al.
Publicado: (2008)

Distinct roles for the hypoxia-inducible transcription factors HIF-1α and HIF-2α in human osteoclast formation and function
por: Knowles, Helen J.
Publicado: (2020)

Twin Resemblance in Muscle HIF-1α Responses to Hypoxia and Exercise
por: Van Thienen, Ruud, et al.
Publicado: (2017)

HIF-1α contributes to hypoxia adaptation of the naked mole rat
por: Xiao, Bang, et al.
Publicado: (2017)

HIF-1α Is Associated with Resistance to Hypoxia-Induced Apoptosis in Ameloblastoma
por: Valladares, Katherine Julissa Palma, et al.
Publicado: (2021)

Role of hypoxia inducible factor HIF-1α in heart valves
por: Georgy, Mark, et al.
Publicado: (2023)

Catabolic stress induces expression of hypoxia-inducible factor (HIF)-1α in articular chondrocytes: involvement of HIF-1α in the pathogenesis of osteoarthritis
por: Yudoh, Kazuo, et al.
Publicado: (2005)

Expression of Hypoxia-Inducible Factor 1α (HIF-1α) and Genes of Related Pathways in Altered Gravity
por: Vogel, Johannes, et al.
Publicado: (2019)

Effects of 2-methoxyestradiol on apoptosis and HIF-1α and HIF-2α expression in lung cancer cells under normoxia and hypoxia
por: AQUINO-GÁLVEZ, ARNOLDO, et al.
Publicado: (2016)

Expression and role of HIF-1α and HIF-2α in tissue regeneration: a study of hypoxia in house gecko tail regeneration
por: Novianti, Titta, et al.
Publicado: (2019)

Hypoxia represses early responses of prostate and renal cancer cells to YM155 independent of HIF-1α and HIF-2α
por: Danielpour, David, et al.
Publicado: (2021)

Correction: Catabolic stress induces expression of hypoxia-inducible factor (HIF)-1α in articular chondrocytes: involvement of HIF-1α in the pathogenesis of osteoarthritis
por: Yudoh, Kazuo, et al.
Publicado: (2005)

The Tyrosine Phosphatase SHP-1 Regulates Hypoxia Inducible Factor-1α (HIF-1α) Protein Levels in Endothelial Cells under Hypoxia
por: Alig, Stefan K., et al.
Publicado: (2015)

Protein Hydroxylation by Hypoxia-Inducible Factor (HIF) Hydroxylases: Unique or Ubiquitous?
por: Strowitzki, Moritz J., et al.
Publicado: (2019)

Defective Mitochondrial Cardiolipin Remodeling Dampens HIF-1α Expression in Hypoxia
por: Chowdhury, Arpita, et al.
Publicado: (2018)

Exercise induces tissue hypoxia and HIF-1α redistribution in the small intestine
por: Wu, Die, et al.
Publicado: (2020)

Hypoxia-Induced Epithelial-Mesenchymal Transition in Cancers: HIF-1α and Beyond
por: Tam, Shing Yau, et al.
Publicado: (2020)

Hypoxia-induced HIF-1α promotes Listeria monocytogenes invasion into tilapia
por: Wang, Jing, et al.
Publicado: (2023)

Inhibition of Hypoxia-Inducible Factor-1α (HIF-1α) Protein Synthesis by DNA Damage Inducing Agents
por: Lou, Jessica Jie Wei, et al.
Publicado: (2010)

Methylation impact analysis of erythropoietin (EPO) Gene to hypoxia inducible factor-1α (HIF-1α) activity
por: Dewi, Firli Rahmah Primula, et al.
Publicado: (2013)

Decreased expression of hypoxia-inducible factor 1α (HIF-1α) in cord blood monocytes under anoxia
por: Schlegel, Christiane, et al.
Publicado: (2022)

Hypoxia-Inducible Factor-1α (HIF-1α) as a Biomarker for Changes in Microcirculation in Individuals with Systemic Sclerosis
por: Maciejewska, Magdalena, et al.
Publicado: (2023)

Hypoxia inducible factor 1α gene (HIF-1α) splice variants: potential prognostic biomarkers in breast cancer
por: Dales, Jean-Philippe, et al.
Publicado: (2010)

Altered Expression of Hypoxia-Inducible Factor-1α (HIF-1α) and Its Regulatory Genes in Gastric Cancer Tissues
por: Wang, Jihan, et al.
Publicado: (2014)

Role of Hypoxia Inducible Factor-1α (HIF-1α) in Innate Defense against Uropathogenic Escherichia coli Infection
por: Lin, Ann E., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_vaooo5nvrqmh7t7ojag21o7jll