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The Guanine Nucleotide Exchange Factor ARNO mediates the activation of ARF and phospholipase D by insulin
BACKGROUND: Phospholipase D (PLD) is involved in many signaling pathways. In most systems, the activity of PLD is primarily regulated by the members of the ADP-Ribosylation Factor (ARF) family of GTPases, but the mechanism of activation of PLD and ARF by extracellular signals has not been fully esta...
Autores principales: | Li, Hai-Sheng, Shome, Kuntala, Rojas, Raúl, Rizzo, Megan A, Vasudevan, Chandrasekaran, Fluharty, Eric, Santy, Lorraine C, Casanova, James E, Romero, Guillermo |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC212319/ https://www.ncbi.nlm.nih.gov/pubmed/12969509 http://dx.doi.org/10.1186/1471-2121-4-13 |
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