A STUDY OF THE CHANGES IN THE BLOOD AND BLOOD-FORMING ORGANS PRODUCED BY CYTOTOXIC SERA, WITH SPECIAL REFERENCE TO HÆMOLYMPHOTOXIN

(1) The cytotoxins are not specific. (2) The changes occurring after the injection of different cytotoxins are similar and do not vary in kind. (3) The changes do, however, vary in degree in the following order, the one having the most marked effect being placed first, etc.: (a) Hæmolymphotoxin, (b)...

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Detalles Bibliográficos
Autor principal: Woltmann, Harro
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1905
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2124566/
https://www.ncbi.nlm.nih.gov/pubmed/19866989
Descripción
Sumario:(1) The cytotoxins are not specific. (2) The changes occurring after the injection of different cytotoxins are similar and do not vary in kind. (3) The changes do, however, vary in degree in the following order, the one having the most marked effect being placed first, etc.: (a) Hæmolymphotoxin, (b) Splenotoxin, (c) Lymphotoxin, (d) Endotheliotoxin, (e) Nephrotoxin, (f) Hepatotoxin. (4) Nephrotoxin causes the most specific change. (5) The hæmolymph glands play some important part in the production of eosinophiles. The hæmolytic action of hæmolymphotoxic serum is greater than that of other cytotoxic sera. (6) The histological changes which are observed in every case are secondary to the hæmolytic factor present in all cytotoxic sera.

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