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AN ATTENUATED SURRA OF MAURITIUS WITH IMMUNITY TESTS AFTER RECOVERY

Apparently as a result of repeated passages through guinea pigs, the virulence of surra of Mauritius for mice became greatly attenuated. Three mice recovered spontaneously and two remained carriers of tryanosomes for four to seven weeks after the parasites were last seen in their blood. The mice tha...

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Detalles Bibliográficos
Autor principal: Terry, B. T.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1910
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2124783/
https://www.ncbi.nlm.nih.gov/pubmed/19867321
Descripción
Sumario:Apparently as a result of repeated passages through guinea pigs, the virulence of surra of Mauritius for mice became greatly attenuated. Three mice recovered spontaneously and two remained carriers of tryanosomes for four to seven weeks after the parasites were last seen in their blood. The mice that recovered acquired no lasting immunity. While the virulence of the parasites decreased for mice, it increased for guinea pigs. By cultivating the parasites in mice the virulence for these animals was restored after four to eight passages.