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A perfect correlate does not a surrogate make
BACKGROUND: There is common belief among some medical researchers that if a potential surrogate endpoint is highly correlated with a true endpoint, then a positive (or negative) difference in potential surrogate endpoints between randomization groups would imply a positive (or negative) difference i...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2003
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC212489/ https://www.ncbi.nlm.nih.gov/pubmed/12962545 http://dx.doi.org/10.1186/1471-2288-3-16 |