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STUDIES IN FERMENT ACTION : II. THE EXTENT OF LEUCOCYTIC PROTEOLYSIS.

This work proves that the proteolytic action of leucocytes is not a simple cleavage by one ferment. There are present two proteases, one acting in an alkaline medium and the other in an acid medium. This confirms Opie's work. In the leucocytes there was found in addition an ereptic ferment whic...

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Detalles Bibliográficos
Autores principales: Jobling, James W., Strouse, Solomon
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1912
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2124965/
https://www.ncbi.nlm.nih.gov/pubmed/19867572
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author Jobling, James W.
Strouse, Solomon
author_facet Jobling, James W.
Strouse, Solomon
author_sort Jobling, James W.
collection PubMed
description This work proves that the proteolytic action of leucocytes is not a simple cleavage by one ferment. There are present two proteases, one acting in an alkaline medium and the other in an acid medium. This confirms Opie's work. In the leucocytes there was found in addition an ereptic ferment which is capable of acting in an acid or alkaline medium. Since this action is lost by heating to 70°C., and by drying and keeping the leucocytes, it probably represents a ferment which acts on the digestion products of the two proteases. Analogy with other ferments in the body confirms this opinion.
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spelling pubmed-21249652008-04-18 STUDIES IN FERMENT ACTION : II. THE EXTENT OF LEUCOCYTIC PROTEOLYSIS. Jobling, James W. Strouse, Solomon J Exp Med Article This work proves that the proteolytic action of leucocytes is not a simple cleavage by one ferment. There are present two proteases, one acting in an alkaline medium and the other in an acid medium. This confirms Opie's work. In the leucocytes there was found in addition an ereptic ferment which is capable of acting in an acid or alkaline medium. Since this action is lost by heating to 70°C., and by drying and keeping the leucocytes, it probably represents a ferment which acts on the digestion products of the two proteases. Analogy with other ferments in the body confirms this opinion. The Rockefeller University Press 1912-09-01 /pmc/articles/PMC2124965/ /pubmed/19867572 Text en Copyright © Copyright, 1912, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Jobling, James W.
Strouse, Solomon
STUDIES IN FERMENT ACTION : II. THE EXTENT OF LEUCOCYTIC PROTEOLYSIS.
title STUDIES IN FERMENT ACTION : II. THE EXTENT OF LEUCOCYTIC PROTEOLYSIS.
title_full STUDIES IN FERMENT ACTION : II. THE EXTENT OF LEUCOCYTIC PROTEOLYSIS.
title_fullStr STUDIES IN FERMENT ACTION : II. THE EXTENT OF LEUCOCYTIC PROTEOLYSIS.
title_full_unstemmed STUDIES IN FERMENT ACTION : II. THE EXTENT OF LEUCOCYTIC PROTEOLYSIS.
title_short STUDIES IN FERMENT ACTION : II. THE EXTENT OF LEUCOCYTIC PROTEOLYSIS.
title_sort studies in ferment action : ii. the extent of leucocytic proteolysis.
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2124965/
https://www.ncbi.nlm.nih.gov/pubmed/19867572
work_keys_str_mv AT joblingjamesw studiesinfermentactioniitheextentofleucocyticproteolysis
AT strousesolomon studiesinfermentactioniitheextentofleucocyticproteolysis