THE ACTION OF PNEUMOCOCCUS ON BLOOD

The reduction of the oxygen capacity which occurs after incubating pneumococcus cultures with washed rabbit corpuscles is due to the formation of methemoglobin (or some derivative of hemoglobin with identical optical constants for three regions in the spectrum). The substance which induces the chang...

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Detalles Bibliográficos
Autores principales: Butterfield, E. E., Peabody, F. W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1913
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2125095/
https://www.ncbi.nlm.nih.gov/pubmed/19867671
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author Butterfield, E. E.
Peabody, F. W.
author_facet Butterfield, E. E.
Peabody, F. W.
author_sort Butterfield, E. E.
collection PubMed
description The reduction of the oxygen capacity which occurs after incubating pneumococcus cultures with washed rabbit corpuscles is due to the formation of methemoglobin (or some derivative of hemoglobin with identical optical constants for three regions in the spectrum). The substance which induces the change is also present in the sterile filtrate of autolyzed cultures. By analogy we feel justified in concluding that the mechanism of the reduction of the oxygen capacity in human lobar pneumonia is at least in part of the same nature. To determine the frequency and intensity of the phenomenon in lobar pneumonia, and thereby to establish its clinical significance, is the next step and a problem upon which we are now engaged.
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spelling pubmed-21250952008-04-18 THE ACTION OF PNEUMOCOCCUS ON BLOOD Butterfield, E. E. Peabody, F. W. J Exp Med Article The reduction of the oxygen capacity which occurs after incubating pneumococcus cultures with washed rabbit corpuscles is due to the formation of methemoglobin (or some derivative of hemoglobin with identical optical constants for three regions in the spectrum). The substance which induces the change is also present in the sterile filtrate of autolyzed cultures. By analogy we feel justified in concluding that the mechanism of the reduction of the oxygen capacity in human lobar pneumonia is at least in part of the same nature. To determine the frequency and intensity of the phenomenon in lobar pneumonia, and thereby to establish its clinical significance, is the next step and a problem upon which we are now engaged. The Rockefeller University Press 1913-05-01 /pmc/articles/PMC2125095/ /pubmed/19867671 Text en Copyright © Copyright, 1913, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Butterfield, E. E.
Peabody, F. W.
THE ACTION OF PNEUMOCOCCUS ON BLOOD
title THE ACTION OF PNEUMOCOCCUS ON BLOOD
title_full THE ACTION OF PNEUMOCOCCUS ON BLOOD
title_fullStr THE ACTION OF PNEUMOCOCCUS ON BLOOD
title_full_unstemmed THE ACTION OF PNEUMOCOCCUS ON BLOOD
title_short THE ACTION OF PNEUMOCOCCUS ON BLOOD
title_sort action of pneumococcus on blood
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2125095/
https://www.ncbi.nlm.nih.gov/pubmed/19867671
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