THE FUNCTION OF THE SPLEEN IN THE EXPERIMENTAL INFECTION OF ALBINO MICE WITH BACILLUS TUBERCULOSIS

Infection of rats and mice with Bacillus tuberculosis (bovine type) develops a splenic tumor as a typical lesion. Removal of the spleen from mice (albino) greatly increases their resistance to the infection. This increased resistance cannot be explained at present. The infection in the splenectomize...

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Detalles Bibliográficos
Autores principales: Lewis, Paul A., Margot, Arthur Georges
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1914
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2125153/
https://www.ncbi.nlm.nih.gov/pubmed/19867757
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author Lewis, Paul A.
Margot, Arthur Georges
author_facet Lewis, Paul A.
Margot, Arthur Georges
author_sort Lewis, Paul A.
collection PubMed
description Infection of rats and mice with Bacillus tuberculosis (bovine type) develops a splenic tumor as a typical lesion. Removal of the spleen from mice (albino) greatly increases their resistance to the infection. This increased resistance cannot be explained at present. The infection in the splenectomized mice tends to remain localized as contrasted with an almost septicemic type of disease which is usual in the normal animal. The animals of each group that live more than thirty days are apt to present typical exudative lesions. The removal of the spleen does not therefore grossly change what may be called the capacity of the body for exudation.
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spelling pubmed-21251532008-04-18 THE FUNCTION OF THE SPLEEN IN THE EXPERIMENTAL INFECTION OF ALBINO MICE WITH BACILLUS TUBERCULOSIS Lewis, Paul A. Margot, Arthur Georges J Exp Med Article Infection of rats and mice with Bacillus tuberculosis (bovine type) develops a splenic tumor as a typical lesion. Removal of the spleen from mice (albino) greatly increases their resistance to the infection. This increased resistance cannot be explained at present. The infection in the splenectomized mice tends to remain localized as contrasted with an almost septicemic type of disease which is usual in the normal animal. The animals of each group that live more than thirty days are apt to present typical exudative lesions. The removal of the spleen does not therefore grossly change what may be called the capacity of the body for exudation. The Rockefeller University Press 1914-02-01 /pmc/articles/PMC2125153/ /pubmed/19867757 Text en Copyright © Copyright, 1914, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Lewis, Paul A.
Margot, Arthur Georges
THE FUNCTION OF THE SPLEEN IN THE EXPERIMENTAL INFECTION OF ALBINO MICE WITH BACILLUS TUBERCULOSIS
title THE FUNCTION OF THE SPLEEN IN THE EXPERIMENTAL INFECTION OF ALBINO MICE WITH BACILLUS TUBERCULOSIS
title_full THE FUNCTION OF THE SPLEEN IN THE EXPERIMENTAL INFECTION OF ALBINO MICE WITH BACILLUS TUBERCULOSIS
title_fullStr THE FUNCTION OF THE SPLEEN IN THE EXPERIMENTAL INFECTION OF ALBINO MICE WITH BACILLUS TUBERCULOSIS
title_full_unstemmed THE FUNCTION OF THE SPLEEN IN THE EXPERIMENTAL INFECTION OF ALBINO MICE WITH BACILLUS TUBERCULOSIS
title_short THE FUNCTION OF THE SPLEEN IN THE EXPERIMENTAL INFECTION OF ALBINO MICE WITH BACILLUS TUBERCULOSIS
title_sort function of the spleen in the experimental infection of albino mice with bacillus tuberculosis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2125153/
https://www.ncbi.nlm.nih.gov/pubmed/19867757
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