A NOTE ON NITROGEN RETENTION FOLLOWING REPEATED INJECTIONS OF NEPHROTOXIC AGENTS

It is possible by means of repeated injections of uranium nitrate to produce in the cat a subacute or chronic nephritis which can progress to a fatal termination and show in its course increasing accumulation of non-protein nitrogen in the blood. This nephritis differs only slightly from the spontan...

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Detalles Bibliográficos
Autores principales: Karsner, Howard T., Denis, W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1914
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2125158/
https://www.ncbi.nlm.nih.gov/pubmed/19867767
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author Karsner, Howard T.
Denis, W.
author_facet Karsner, Howard T.
Denis, W.
author_sort Karsner, Howard T.
collection PubMed
description It is possible by means of repeated injections of uranium nitrate to produce in the cat a subacute or chronic nephritis which can progress to a fatal termination and show in its course increasing accumulation of non-protein nitrogen in the blood. This nephritis differs only slightly from the spontaneous chronic nephritis of the species. Repeated doses of diphtheria toxin produce a subacute form of nephritis with only temporary or slight retention, but nevertheless anatomically a well defined nephritis. The spontaneous nephritis studied resembles more closely that produced by uranium nitrate than that produced by diphtheria toxin both histologically and from the standpoint of blood analysis.
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spelling pubmed-21251582008-04-18 A NOTE ON NITROGEN RETENTION FOLLOWING REPEATED INJECTIONS OF NEPHROTOXIC AGENTS Karsner, Howard T. Denis, W. J Exp Med Article It is possible by means of repeated injections of uranium nitrate to produce in the cat a subacute or chronic nephritis which can progress to a fatal termination and show in its course increasing accumulation of non-protein nitrogen in the blood. This nephritis differs only slightly from the spontaneous chronic nephritis of the species. Repeated doses of diphtheria toxin produce a subacute form of nephritis with only temporary or slight retention, but nevertheless anatomically a well defined nephritis. The spontaneous nephritis studied resembles more closely that produced by uranium nitrate than that produced by diphtheria toxin both histologically and from the standpoint of blood analysis. The Rockefeller University Press 1914-03-01 /pmc/articles/PMC2125158/ /pubmed/19867767 Text en Copyright © Copyright, 1914, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Karsner, Howard T.
Denis, W.
A NOTE ON NITROGEN RETENTION FOLLOWING REPEATED INJECTIONS OF NEPHROTOXIC AGENTS
title A NOTE ON NITROGEN RETENTION FOLLOWING REPEATED INJECTIONS OF NEPHROTOXIC AGENTS
title_full A NOTE ON NITROGEN RETENTION FOLLOWING REPEATED INJECTIONS OF NEPHROTOXIC AGENTS
title_fullStr A NOTE ON NITROGEN RETENTION FOLLOWING REPEATED INJECTIONS OF NEPHROTOXIC AGENTS
title_full_unstemmed A NOTE ON NITROGEN RETENTION FOLLOWING REPEATED INJECTIONS OF NEPHROTOXIC AGENTS
title_short A NOTE ON NITROGEN RETENTION FOLLOWING REPEATED INJECTIONS OF NEPHROTOXIC AGENTS
title_sort note on nitrogen retention following repeated injections of nephrotoxic agents
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2125158/
https://www.ncbi.nlm.nih.gov/pubmed/19867767
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