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FURTHER EXPERIMENTS UPON THE EFFECTS OF EXTIRPATION OF THE THYMUS IN RATS, WITH SPECIAL REFERENCE TO THE ALLEGED PRODUCTION OF RACHITIC LESIONS
Rachitic changes in the bones and teeth occur in young albino rats as the result of spontaneous disease, possibly of infective origin. This disease is often, but not always, accompanied by an arrest of growth and malnutrition. There is no valid reason for attributing such lesions to the loss of thym...
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1914
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2125202/ https://www.ncbi.nlm.nih.gov/pubmed/19867836 |
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author | Pappenheimer, Alwin M. |
author_facet | Pappenheimer, Alwin M. |
author_sort | Pappenheimer, Alwin M. |
collection | PubMed |
description | Rachitic changes in the bones and teeth occur in young albino rats as the result of spontaneous disease, possibly of infective origin. This disease is often, but not always, accompanied by an arrest of growth and malnutrition. There is no valid reason for attributing such lesions to the loss of thymic function. In some of the rats showing the disease, an unusual number of mitoses were found in the parathyroid glands, but no evidence of injury to these structures. It has not been found possible to confirm the statements of Klose and Magnini as to the fatal effects of complete thymus extirpation in rats. |
format | Text |
id | pubmed-2125202 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1914 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21252022008-04-18 FURTHER EXPERIMENTS UPON THE EFFECTS OF EXTIRPATION OF THE THYMUS IN RATS, WITH SPECIAL REFERENCE TO THE ALLEGED PRODUCTION OF RACHITIC LESIONS Pappenheimer, Alwin M. J Exp Med Article Rachitic changes in the bones and teeth occur in young albino rats as the result of spontaneous disease, possibly of infective origin. This disease is often, but not always, accompanied by an arrest of growth and malnutrition. There is no valid reason for attributing such lesions to the loss of thymic function. In some of the rats showing the disease, an unusual number of mitoses were found in the parathyroid glands, but no evidence of injury to these structures. It has not been found possible to confirm the statements of Klose and Magnini as to the fatal effects of complete thymus extirpation in rats. The Rockefeller University Press 1914-11-01 /pmc/articles/PMC2125202/ /pubmed/19867836 Text en Copyright © Copyright, 1914, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Pappenheimer, Alwin M. FURTHER EXPERIMENTS UPON THE EFFECTS OF EXTIRPATION OF THE THYMUS IN RATS, WITH SPECIAL REFERENCE TO THE ALLEGED PRODUCTION OF RACHITIC LESIONS |
title | FURTHER EXPERIMENTS UPON THE EFFECTS OF EXTIRPATION OF THE THYMUS IN RATS, WITH SPECIAL REFERENCE TO THE ALLEGED PRODUCTION OF RACHITIC LESIONS |
title_full | FURTHER EXPERIMENTS UPON THE EFFECTS OF EXTIRPATION OF THE THYMUS IN RATS, WITH SPECIAL REFERENCE TO THE ALLEGED PRODUCTION OF RACHITIC LESIONS |
title_fullStr | FURTHER EXPERIMENTS UPON THE EFFECTS OF EXTIRPATION OF THE THYMUS IN RATS, WITH SPECIAL REFERENCE TO THE ALLEGED PRODUCTION OF RACHITIC LESIONS |
title_full_unstemmed | FURTHER EXPERIMENTS UPON THE EFFECTS OF EXTIRPATION OF THE THYMUS IN RATS, WITH SPECIAL REFERENCE TO THE ALLEGED PRODUCTION OF RACHITIC LESIONS |
title_short | FURTHER EXPERIMENTS UPON THE EFFECTS OF EXTIRPATION OF THE THYMUS IN RATS, WITH SPECIAL REFERENCE TO THE ALLEGED PRODUCTION OF RACHITIC LESIONS |
title_sort | further experiments upon the effects of extirpation of the thymus in rats, with special reference to the alleged production of rachitic lesions |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2125202/ https://www.ncbi.nlm.nih.gov/pubmed/19867836 |
work_keys_str_mv | AT pappenheimeralwinm furtherexperimentsupontheeffectsofextirpationofthethymusinratswithspecialreferencetotheallegedproductionofrachiticlesions |