CONCENTRATION OF THE PROTECTIVE BODIES IN ANTIPNEUMOCOCCUS SERUM BY MEANS OF SPECIFIC PRECIPITATION

The addition of a water-clear extract of pneumococci to homologous antiserum produces a voluminous precipitate which carries down with it the agglutinins and practically the totality of the protective bodies against pneumococcus infection in animals. This precipitate when washed and resuspended in s...

Descripción completa

Detalles Bibliográficos
Autores principales: Gay, Frederick P., Chickering, Henry T.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1915
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2125319/
https://www.ncbi.nlm.nih.gov/pubmed/19867879
_version_ 1782141868843204608
author Gay, Frederick P.
Chickering, Henry T.
author_facet Gay, Frederick P.
Chickering, Henry T.
author_sort Gay, Frederick P.
collection PubMed
description The addition of a water-clear extract of pneumococci to homologous antiserum produces a voluminous precipitate which carries down with it the agglutinins and practically the totality of the protective bodies against pneumococcus infection in animals. This precipitate when washed and resuspended in saline solution to the original volume of serum protects as well as the whole serum. The protein content of such solutions has varied from 0.09 to 0.34 per cent., as contrasted with about 6 per cent. in the original serum. The solution of this precipitate is not necessary to insure protection, and when produced by dilute alkali (sodium hydrate) frequently destroys the immune bodies.
format Text
id pubmed-2125319
institution National Center for Biotechnology Information
language English
publishDate 1915
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21253192008-04-18 CONCENTRATION OF THE PROTECTIVE BODIES IN ANTIPNEUMOCOCCUS SERUM BY MEANS OF SPECIFIC PRECIPITATION Gay, Frederick P. Chickering, Henry T. J Exp Med Article The addition of a water-clear extract of pneumococci to homologous antiserum produces a voluminous precipitate which carries down with it the agglutinins and practically the totality of the protective bodies against pneumococcus infection in animals. This precipitate when washed and resuspended in saline solution to the original volume of serum protects as well as the whole serum. The protein content of such solutions has varied from 0.09 to 0.34 per cent., as contrasted with about 6 per cent. in the original serum. The solution of this precipitate is not necessary to insure protection, and when produced by dilute alkali (sodium hydrate) frequently destroys the immune bodies. The Rockefeller University Press 1915-04-01 /pmc/articles/PMC2125319/ /pubmed/19867879 Text en Copyright © Copyright, 1915, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Gay, Frederick P.
Chickering, Henry T.
CONCENTRATION OF THE PROTECTIVE BODIES IN ANTIPNEUMOCOCCUS SERUM BY MEANS OF SPECIFIC PRECIPITATION
title CONCENTRATION OF THE PROTECTIVE BODIES IN ANTIPNEUMOCOCCUS SERUM BY MEANS OF SPECIFIC PRECIPITATION
title_full CONCENTRATION OF THE PROTECTIVE BODIES IN ANTIPNEUMOCOCCUS SERUM BY MEANS OF SPECIFIC PRECIPITATION
title_fullStr CONCENTRATION OF THE PROTECTIVE BODIES IN ANTIPNEUMOCOCCUS SERUM BY MEANS OF SPECIFIC PRECIPITATION
title_full_unstemmed CONCENTRATION OF THE PROTECTIVE BODIES IN ANTIPNEUMOCOCCUS SERUM BY MEANS OF SPECIFIC PRECIPITATION
title_short CONCENTRATION OF THE PROTECTIVE BODIES IN ANTIPNEUMOCOCCUS SERUM BY MEANS OF SPECIFIC PRECIPITATION
title_sort concentration of the protective bodies in antipneumococcus serum by means of specific precipitation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2125319/
https://www.ncbi.nlm.nih.gov/pubmed/19867879
work_keys_str_mv AT gayfrederickp concentrationoftheprotectivebodiesinantipneumococcusserumbymeansofspecificprecipitation
AT chickeringhenryt concentrationoftheprotectivebodiesinantipneumococcusserumbymeansofspecificprecipitation

Ejemplares similares