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THE MECHANISM OF THE CURATIVE ACTION OF ANTIPNEUMOCOCCUS SERUM

An active antipneumococcus serum causes agglutination of pneumococci in vitro and in vivo. The antiserum acts in far greater dilution in causing agglutination as determined by the microscopic than by the macroscopic test. The antiserum when injected into the circulation of rabbits suffering from pne...

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Detalles Bibliográficos
Autor principal: Bull, Carroll G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1915
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2125359/
https://www.ncbi.nlm.nih.gov/pubmed/19867929
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author Bull, Carroll G.
author_facet Bull, Carroll G.
author_sort Bull, Carroll G.
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description An active antipneumococcus serum causes agglutination of pneumococci in vitro and in vivo. The antiserum acts in far greater dilution in causing agglutination as determined by the microscopic than by the macroscopic test. The antiserum when injected into the circulation of rabbits suffering from pneumococcus bacteremia causes a rapid disappearance of the diplococci from the blood. This disappearance is brought about by instantaneous clumping of the diplococci in vivo and the removal of the clumps by the liver, spleen, lungs, and possibly other organs.
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spelling pubmed-21253592008-04-18 THE MECHANISM OF THE CURATIVE ACTION OF ANTIPNEUMOCOCCUS SERUM Bull, Carroll G. J Exp Med Article An active antipneumococcus serum causes agglutination of pneumococci in vitro and in vivo. The antiserum acts in far greater dilution in causing agglutination as determined by the microscopic than by the macroscopic test. The antiserum when injected into the circulation of rabbits suffering from pneumococcus bacteremia causes a rapid disappearance of the diplococci from the blood. This disappearance is brought about by instantaneous clumping of the diplococci in vivo and the removal of the clumps by the liver, spleen, lungs, and possibly other organs. The Rockefeller University Press 1915-10-01 /pmc/articles/PMC2125359/ /pubmed/19867929 Text en Copyright © Copyright, 1915, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Bull, Carroll G.
THE MECHANISM OF THE CURATIVE ACTION OF ANTIPNEUMOCOCCUS SERUM
title THE MECHANISM OF THE CURATIVE ACTION OF ANTIPNEUMOCOCCUS SERUM
title_full THE MECHANISM OF THE CURATIVE ACTION OF ANTIPNEUMOCOCCUS SERUM
title_fullStr THE MECHANISM OF THE CURATIVE ACTION OF ANTIPNEUMOCOCCUS SERUM
title_full_unstemmed THE MECHANISM OF THE CURATIVE ACTION OF ANTIPNEUMOCOCCUS SERUM
title_short THE MECHANISM OF THE CURATIVE ACTION OF ANTIPNEUMOCOCCUS SERUM
title_sort mechanism of the curative action of antipneumococcus serum
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2125359/
https://www.ncbi.nlm.nih.gov/pubmed/19867929
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