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THE MECHANISM OF THE CURATIVE ACTION OF ANTIPNEUMOCOCCUS SERUM
An active antipneumococcus serum causes agglutination of pneumococci in vitro and in vivo. The antiserum acts in far greater dilution in causing agglutination as determined by the microscopic than by the macroscopic test. The antiserum when injected into the circulation of rabbits suffering from pne...
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1915
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2125359/ https://www.ncbi.nlm.nih.gov/pubmed/19867929 |
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author | Bull, Carroll G. |
author_facet | Bull, Carroll G. |
author_sort | Bull, Carroll G. |
collection | PubMed |
description | An active antipneumococcus serum causes agglutination of pneumococci in vitro and in vivo. The antiserum acts in far greater dilution in causing agglutination as determined by the microscopic than by the macroscopic test. The antiserum when injected into the circulation of rabbits suffering from pneumococcus bacteremia causes a rapid disappearance of the diplococci from the blood. This disappearance is brought about by instantaneous clumping of the diplococci in vivo and the removal of the clumps by the liver, spleen, lungs, and possibly other organs. |
format | Text |
id | pubmed-2125359 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1915 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21253592008-04-18 THE MECHANISM OF THE CURATIVE ACTION OF ANTIPNEUMOCOCCUS SERUM Bull, Carroll G. J Exp Med Article An active antipneumococcus serum causes agglutination of pneumococci in vitro and in vivo. The antiserum acts in far greater dilution in causing agglutination as determined by the microscopic than by the macroscopic test. The antiserum when injected into the circulation of rabbits suffering from pneumococcus bacteremia causes a rapid disappearance of the diplococci from the blood. This disappearance is brought about by instantaneous clumping of the diplococci in vivo and the removal of the clumps by the liver, spleen, lungs, and possibly other organs. The Rockefeller University Press 1915-10-01 /pmc/articles/PMC2125359/ /pubmed/19867929 Text en Copyright © Copyright, 1915, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Bull, Carroll G. THE MECHANISM OF THE CURATIVE ACTION OF ANTIPNEUMOCOCCUS SERUM |
title | THE MECHANISM OF THE CURATIVE ACTION OF ANTIPNEUMOCOCCUS SERUM |
title_full | THE MECHANISM OF THE CURATIVE ACTION OF ANTIPNEUMOCOCCUS SERUM |
title_fullStr | THE MECHANISM OF THE CURATIVE ACTION OF ANTIPNEUMOCOCCUS SERUM |
title_full_unstemmed | THE MECHANISM OF THE CURATIVE ACTION OF ANTIPNEUMOCOCCUS SERUM |
title_short | THE MECHANISM OF THE CURATIVE ACTION OF ANTIPNEUMOCOCCUS SERUM |
title_sort | mechanism of the curative action of antipneumococcus serum |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2125359/ https://www.ncbi.nlm.nih.gov/pubmed/19867929 |
work_keys_str_mv | AT bullcarrollg themechanismofthecurativeactionofantipneumococcusserum AT bullcarrollg mechanismofthecurativeactionofantipneumococcusserum |