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EXPERIMENTAL ARTHRITIS IN THE RABBIT. A CONTRIBUTION TO THE PATHOGENY OF ARTHRITIS IN RHEUMATIC FEVER
By a process of sensitization described it was found possible to cause arthritis in rabbits constantly after one intravenous injection of the streptococcus. This reaction is specific. By intravenous inoculation, without previous sensitization, of the streptococcus used in these experiments it was po...
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1915
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2125371/ https://www.ncbi.nlm.nih.gov/pubmed/19867944 |
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author | Faber, Harold Kniest |
author_facet | Faber, Harold Kniest |
author_sort | Faber, Harold Kniest |
collection | PubMed |
description | By a process of sensitization described it was found possible to cause arthritis in rabbits constantly after one intravenous injection of the streptococcus. This reaction is specific. By intravenous inoculation, without previous sensitization, of the streptococcus used in these experiments it was possible to cause arthritis in rabbits only after three or more injections. An analogy is suggested between the arthritis induced by sensitization and the relapses in human rheumatic fever. A further analogy is suggested between the development in rabbits of arthritis after repeated intravenous injections and the development of the primary lesion in human rheumatic fever. |
format | Text |
id | pubmed-2125371 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1915 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21253712008-04-18 EXPERIMENTAL ARTHRITIS IN THE RABBIT. A CONTRIBUTION TO THE PATHOGENY OF ARTHRITIS IN RHEUMATIC FEVER Faber, Harold Kniest J Exp Med Article By a process of sensitization described it was found possible to cause arthritis in rabbits constantly after one intravenous injection of the streptococcus. This reaction is specific. By intravenous inoculation, without previous sensitization, of the streptococcus used in these experiments it was possible to cause arthritis in rabbits only after three or more injections. An analogy is suggested between the arthritis induced by sensitization and the relapses in human rheumatic fever. A further analogy is suggested between the development in rabbits of arthritis after repeated intravenous injections and the development of the primary lesion in human rheumatic fever. The Rockefeller University Press 1915-11-01 /pmc/articles/PMC2125371/ /pubmed/19867944 Text en Copyright © Copyright, 1915, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Faber, Harold Kniest EXPERIMENTAL ARTHRITIS IN THE RABBIT. A CONTRIBUTION TO THE PATHOGENY OF ARTHRITIS IN RHEUMATIC FEVER |
title | EXPERIMENTAL ARTHRITIS IN THE RABBIT. A CONTRIBUTION TO THE PATHOGENY OF ARTHRITIS IN RHEUMATIC FEVER |
title_full | EXPERIMENTAL ARTHRITIS IN THE RABBIT. A CONTRIBUTION TO THE PATHOGENY OF ARTHRITIS IN RHEUMATIC FEVER |
title_fullStr | EXPERIMENTAL ARTHRITIS IN THE RABBIT. A CONTRIBUTION TO THE PATHOGENY OF ARTHRITIS IN RHEUMATIC FEVER |
title_full_unstemmed | EXPERIMENTAL ARTHRITIS IN THE RABBIT. A CONTRIBUTION TO THE PATHOGENY OF ARTHRITIS IN RHEUMATIC FEVER |
title_short | EXPERIMENTAL ARTHRITIS IN THE RABBIT. A CONTRIBUTION TO THE PATHOGENY OF ARTHRITIS IN RHEUMATIC FEVER |
title_sort | experimental arthritis in the rabbit. a contribution to the pathogeny of arthritis in rheumatic fever |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2125371/ https://www.ncbi.nlm.nih.gov/pubmed/19867944 |
work_keys_str_mv | AT faberharoldkniest experimentalarthritisintherabbitacontributiontothepathogenyofarthritisinrheumaticfever |