STUDIES ON HETEROGENEOUS HEMOLYTIC SERA

Red corpuscles with nuclei contain heterogeneous sheep antigen when the organs of the same animal possess it. The sera in question contain not only heterogeneous hemolysins but also heterogeneous agglutinins. The hemolytic sera of rabbits immunized with hen red corpuscles are toxic to guinea pigs an...

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Detalles Bibliográficos
Autor principal: Kritchevsky, I. L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1916
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2125405/
https://www.ncbi.nlm.nih.gov/pubmed/19868038
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author Kritchevsky, I. L.
author_facet Kritchevsky, I. L.
author_sort Kritchevsky, I. L.
collection PubMed
description Red corpuscles with nuclei contain heterogeneous sheep antigen when the organs of the same animal possess it. The sera in question contain not only heterogeneous hemolysins but also heterogeneous agglutinins. The hemolytic sera of rabbits immunized with hen red corpuscles are toxic to guinea pigs and kill them, the clinical picture being that of anaphylactic shock. Heterogeneous hemolysins are obtained by means of non-toxic antigen (hen red corpuscles injected into veins of rabbits). This fact refutes the theory of Friedberger, who attributed the antigenic power of a suspension of organs to its toxic character.
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spelling pubmed-21254052008-04-18 STUDIES ON HETEROGENEOUS HEMOLYTIC SERA Kritchevsky, I. L. J Exp Med Article Red corpuscles with nuclei contain heterogeneous sheep antigen when the organs of the same animal possess it. The sera in question contain not only heterogeneous hemolysins but also heterogeneous agglutinins. The hemolytic sera of rabbits immunized with hen red corpuscles are toxic to guinea pigs and kill them, the clinical picture being that of anaphylactic shock. Heterogeneous hemolysins are obtained by means of non-toxic antigen (hen red corpuscles injected into veins of rabbits). This fact refutes the theory of Friedberger, who attributed the antigenic power of a suspension of organs to its toxic character. The Rockefeller University Press 1916-09-01 /pmc/articles/PMC2125405/ /pubmed/19868038 Text en Copyright © Copyright, 1916, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Kritchevsky, I. L.
STUDIES ON HETEROGENEOUS HEMOLYTIC SERA
title STUDIES ON HETEROGENEOUS HEMOLYTIC SERA
title_full STUDIES ON HETEROGENEOUS HEMOLYTIC SERA
title_fullStr STUDIES ON HETEROGENEOUS HEMOLYTIC SERA
title_full_unstemmed STUDIES ON HETEROGENEOUS HEMOLYTIC SERA
title_short STUDIES ON HETEROGENEOUS HEMOLYTIC SERA
title_sort studies on heterogeneous hemolytic sera
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2125405/
https://www.ncbi.nlm.nih.gov/pubmed/19868038
work_keys_str_mv AT kritchevskyil studiesonheterogeneoushemolyticsera

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