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THE EFFECTS OF SERUM TREATED WITH AGAR
The intravenous injection of horse serum, kept for 2 hours at 38°C. in the presence of one-fifth of its volume of a suspension of 0.5 per cent agar in physiological salt solution and then separated from the agar by centrifugalization and filtration, produces in normal rabbits in adequate doses a con...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1916
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2125407/ https://www.ncbi.nlm.nih.gov/pubmed/19868039 |
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author | Zunz, Edgard Gelat, Maurice |
author_facet | Zunz, Edgard Gelat, Maurice |
author_sort | Zunz, Edgard |
collection | PubMed |
description | The intravenous injection of horse serum, kept for 2 hours at 38°C. in the presence of one-fifth of its volume of a suspension of 0.5 per cent agar in physiological salt solution and then separated from the agar by centrifugalization and filtration, produces in normal rabbits in adequate doses a considerable and prolonged fall in the blood pressure, expulsion of feces, a diminished coagulability in the carotid blood, and at times accelerated respiration; that is, the various symptoms observed after the intravenous injection of horse serum in a seroanaphylactized rabbit. Horse serum previously kept for 30 minutes at 56°C. and then treated with agar in the manner described above, when injected intravenously into a normal rabbit will have no more effect on the arterial pressure, on the intestinal movement, on the respiratory rate, or the coagulation of arterial blood than the introduction of horse serum into the veins of a normal rabbit. |
format | Text |
id | pubmed-2125407 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1916 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21254072008-04-18 THE EFFECTS OF SERUM TREATED WITH AGAR Zunz, Edgard Gelat, Maurice J Exp Med Article The intravenous injection of horse serum, kept for 2 hours at 38°C. in the presence of one-fifth of its volume of a suspension of 0.5 per cent agar in physiological salt solution and then separated from the agar by centrifugalization and filtration, produces in normal rabbits in adequate doses a considerable and prolonged fall in the blood pressure, expulsion of feces, a diminished coagulability in the carotid blood, and at times accelerated respiration; that is, the various symptoms observed after the intravenous injection of horse serum in a seroanaphylactized rabbit. Horse serum previously kept for 30 minutes at 56°C. and then treated with agar in the manner described above, when injected intravenously into a normal rabbit will have no more effect on the arterial pressure, on the intestinal movement, on the respiratory rate, or the coagulation of arterial blood than the introduction of horse serum into the veins of a normal rabbit. The Rockefeller University Press 1916-09-01 /pmc/articles/PMC2125407/ /pubmed/19868039 Text en Copyright © Copyright, 1916, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Zunz, Edgard Gelat, Maurice THE EFFECTS OF SERUM TREATED WITH AGAR |
title | THE EFFECTS OF SERUM TREATED WITH AGAR |
title_full | THE EFFECTS OF SERUM TREATED WITH AGAR |
title_fullStr | THE EFFECTS OF SERUM TREATED WITH AGAR |
title_full_unstemmed | THE EFFECTS OF SERUM TREATED WITH AGAR |
title_short | THE EFFECTS OF SERUM TREATED WITH AGAR |
title_sort | effects of serum treated with agar |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2125407/ https://www.ncbi.nlm.nih.gov/pubmed/19868039 |
work_keys_str_mv | AT zunzedgard theeffectsofserumtreatedwithagar AT gelatmaurice theeffectsofserumtreatedwithagar AT zunzedgard effectsofserumtreatedwithagar AT gelatmaurice effectsofserumtreatedwithagar |