STUDIES IN GLOMERULONEPHRITIS : II. A FORM OF ACUTE GLOMERULONEPHRITIS PRODUCED WITH DIPHTHERIA TOXIN AND BACILLUS COLI.

1. Rabbits in which a mild grade of glomerular damage has been produced by small doses of diphtheria toxin develop a severe glomerulonephritis corresponding to the extracapillary form described by Volhard and Fahr after inoculations with sublethal quantities of Bacillus coli. 2. Similar, though not...

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Detalles Bibliográficos
Autor principal: Faber, Harold Kniest
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1917
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2125653/
https://www.ncbi.nlm.nih.gov/pubmed/19868142
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author Faber, Harold Kniest
author_facet Faber, Harold Kniest
author_sort Faber, Harold Kniest
collection PubMed
description 1. Rabbits in which a mild grade of glomerular damage has been produced by small doses of diphtheria toxin develop a severe glomerulonephritis corresponding to the extracapillary form described by Volhard and Fahr after inoculations with sublethal quantities of Bacillus coli. 2. Similar, though not completely identical lesions are produced when diphtheria toxin is followed by intravenous injections of Vaughan's split protein (poisonous part) of Bacillus coli. 3. The inference is drawn that under the experimental conditions described Bacillus coli undergoes bacteriolysis and produces glomerular lesions through the toxic groups contained within its protein molecule.
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spelling pubmed-21256532008-04-18 STUDIES IN GLOMERULONEPHRITIS : II. A FORM OF ACUTE GLOMERULONEPHRITIS PRODUCED WITH DIPHTHERIA TOXIN AND BACILLUS COLI. Faber, Harold Kniest J Exp Med Article 1. Rabbits in which a mild grade of glomerular damage has been produced by small doses of diphtheria toxin develop a severe glomerulonephritis corresponding to the extracapillary form described by Volhard and Fahr after inoculations with sublethal quantities of Bacillus coli. 2. Similar, though not completely identical lesions are produced when diphtheria toxin is followed by intravenous injections of Vaughan's split protein (poisonous part) of Bacillus coli. 3. The inference is drawn that under the experimental conditions described Bacillus coli undergoes bacteriolysis and produces glomerular lesions through the toxic groups contained within its protein molecule. The Rockefeller University Press 1917-08-01 /pmc/articles/PMC2125653/ /pubmed/19868142 Text en Copyright © Copyright, 1917, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Faber, Harold Kniest
STUDIES IN GLOMERULONEPHRITIS : II. A FORM OF ACUTE GLOMERULONEPHRITIS PRODUCED WITH DIPHTHERIA TOXIN AND BACILLUS COLI.
title STUDIES IN GLOMERULONEPHRITIS : II. A FORM OF ACUTE GLOMERULONEPHRITIS PRODUCED WITH DIPHTHERIA TOXIN AND BACILLUS COLI.
title_full STUDIES IN GLOMERULONEPHRITIS : II. A FORM OF ACUTE GLOMERULONEPHRITIS PRODUCED WITH DIPHTHERIA TOXIN AND BACILLUS COLI.
title_fullStr STUDIES IN GLOMERULONEPHRITIS : II. A FORM OF ACUTE GLOMERULONEPHRITIS PRODUCED WITH DIPHTHERIA TOXIN AND BACILLUS COLI.
title_full_unstemmed STUDIES IN GLOMERULONEPHRITIS : II. A FORM OF ACUTE GLOMERULONEPHRITIS PRODUCED WITH DIPHTHERIA TOXIN AND BACILLUS COLI.
title_short STUDIES IN GLOMERULONEPHRITIS : II. A FORM OF ACUTE GLOMERULONEPHRITIS PRODUCED WITH DIPHTHERIA TOXIN AND BACILLUS COLI.
title_sort studies in glomerulonephritis : ii. a form of acute glomerulonephritis produced with diphtheria toxin and bacillus coli.
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2125653/
https://www.ncbi.nlm.nih.gov/pubmed/19868142
work_keys_str_mv AT faberharoldkniest studiesinglomerulonephritisiiaformofacuteglomerulonephritisproducedwithdiphtheriatoxinandbacilluscoli

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