EXPERIMENTAL ACUTE NEPHRITIS : A STUDY OF THE ACIDOSIS, NITROGEN AND CHLORIDE RETENTION, AND OF THE PROTECTIVE ACTION OF SODIUM BICARBONATE.

1. In experimental nephritis caused by cantharidin, arsenic, diphtheria toxin, and potassium chromate, in addition to the retention of the non-protein and urea nitrogen and of the chlorides in blood, an acidosis occurs. 2. Sodium bicarbonate given by the stomach has the power of diminishing the acid...

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Detalles Bibliográficos
Autor principal: Goto, Kingo
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1918
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2125967/
https://www.ncbi.nlm.nih.gov/pubmed/19868214
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author Goto, Kingo
author_facet Goto, Kingo
author_sort Goto, Kingo
collection PubMed
description 1. In experimental nephritis caused by cantharidin, arsenic, diphtheria toxin, and potassium chromate, in addition to the retention of the non-protein and urea nitrogen and of the chlorides in blood, an acidosis occurs. 2. Sodium bicarbonate given by the stomach has the power of diminishing the acidosis in these types of nephritis. 3. The degree of increase in the non-protein and urea nitrogen content in the blood in mild nephritis varies considerably in different dogs receiving the same dose per kilo of a given poison. 4. Histological examination shows little if any influence resulting from the administration of sodium bicarbonate upon the grade of the nephritis induced by the poisons.
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spelling pubmed-21259672008-04-18 EXPERIMENTAL ACUTE NEPHRITIS : A STUDY OF THE ACIDOSIS, NITROGEN AND CHLORIDE RETENTION, AND OF THE PROTECTIVE ACTION OF SODIUM BICARBONATE. Goto, Kingo J Exp Med Article 1. In experimental nephritis caused by cantharidin, arsenic, diphtheria toxin, and potassium chromate, in addition to the retention of the non-protein and urea nitrogen and of the chlorides in blood, an acidosis occurs. 2. Sodium bicarbonate given by the stomach has the power of diminishing the acidosis in these types of nephritis. 3. The degree of increase in the non-protein and urea nitrogen content in the blood in mild nephritis varies considerably in different dogs receiving the same dose per kilo of a given poison. 4. Histological examination shows little if any influence resulting from the administration of sodium bicarbonate upon the grade of the nephritis induced by the poisons. The Rockefeller University Press 1918-03-01 /pmc/articles/PMC2125967/ /pubmed/19868214 Text en Copyright © Copyright, 1918, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Goto, Kingo
EXPERIMENTAL ACUTE NEPHRITIS : A STUDY OF THE ACIDOSIS, NITROGEN AND CHLORIDE RETENTION, AND OF THE PROTECTIVE ACTION OF SODIUM BICARBONATE.
title EXPERIMENTAL ACUTE NEPHRITIS : A STUDY OF THE ACIDOSIS, NITROGEN AND CHLORIDE RETENTION, AND OF THE PROTECTIVE ACTION OF SODIUM BICARBONATE.
title_full EXPERIMENTAL ACUTE NEPHRITIS : A STUDY OF THE ACIDOSIS, NITROGEN AND CHLORIDE RETENTION, AND OF THE PROTECTIVE ACTION OF SODIUM BICARBONATE.
title_fullStr EXPERIMENTAL ACUTE NEPHRITIS : A STUDY OF THE ACIDOSIS, NITROGEN AND CHLORIDE RETENTION, AND OF THE PROTECTIVE ACTION OF SODIUM BICARBONATE.
title_full_unstemmed EXPERIMENTAL ACUTE NEPHRITIS : A STUDY OF THE ACIDOSIS, NITROGEN AND CHLORIDE RETENTION, AND OF THE PROTECTIVE ACTION OF SODIUM BICARBONATE.
title_short EXPERIMENTAL ACUTE NEPHRITIS : A STUDY OF THE ACIDOSIS, NITROGEN AND CHLORIDE RETENTION, AND OF THE PROTECTIVE ACTION OF SODIUM BICARBONATE.
title_sort experimental acute nephritis : a study of the acidosis, nitrogen and chloride retention, and of the protective action of sodium bicarbonate.
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2125967/
https://www.ncbi.nlm.nih.gov/pubmed/19868214
work_keys_str_mv AT gotokingo experimentalacutenephritisastudyoftheacidosisnitrogenandchlorideretentionandoftheprotectiveactionofsodiumbicarbonate

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