Cargando…
THE STABILITY OF THE ACID-BASE EQUILIBRIUM OF THE BLOOD IN NATURALLY NEPHROPATHIC ANIMALS AND THE EFFECT ON RENAL FUNCTION OF CHANGES IN THIS EQUILIBRIUM : II. A STUDY OF THE EFFICIENCY OF AN ALKALI TO PROTECT THE NATURALLY NEPHROPATHIC KIDNEY AGAINST THE TOXIC EFFECT OF AN ANESTHETIC.
1. A 0.9 per cent solution of sodium chloride when given intravenously to anesthetized naturally nephropathic animals is not effective in preventing the development of an acid intoxication and the associated kidney injury. 2. A solution of sodium carbonate equimolecular with a 0.9 per cent solution...
Autor principal: | |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1918
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2126284/ https://www.ncbi.nlm.nih.gov/pubmed/19868273 |
_version_ | 1782141955700948992 |
---|---|
author | MacNider, William deB. |
author_facet | MacNider, William deB. |
author_sort | MacNider, William deB. |
collection | PubMed |
description | 1. A 0.9 per cent solution of sodium chloride when given intravenously to anesthetized naturally nephropathic animals is not effective in preventing the development of an acid intoxication and the associated kidney injury. 2. A solution of sodium carbonate equimolecular with a 0.9 per cent solution of sodium chloride when given intravenously to anesthetized naturally nephropathic animals confers a variable degree of protection to the kidney. 3. The degree of protection conferred by the alkaline solution is associated with the ability of the solution to maintain a normal acid-base equilibrium of the blood of the anesthetized animal. |
format | Text |
id | pubmed-2126284 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1918 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21262842008-04-18 THE STABILITY OF THE ACID-BASE EQUILIBRIUM OF THE BLOOD IN NATURALLY NEPHROPATHIC ANIMALS AND THE EFFECT ON RENAL FUNCTION OF CHANGES IN THIS EQUILIBRIUM : II. A STUDY OF THE EFFICIENCY OF AN ALKALI TO PROTECT THE NATURALLY NEPHROPATHIC KIDNEY AGAINST THE TOXIC EFFECT OF AN ANESTHETIC. MacNider, William deB. J Exp Med Article 1. A 0.9 per cent solution of sodium chloride when given intravenously to anesthetized naturally nephropathic animals is not effective in preventing the development of an acid intoxication and the associated kidney injury. 2. A solution of sodium carbonate equimolecular with a 0.9 per cent solution of sodium chloride when given intravenously to anesthetized naturally nephropathic animals confers a variable degree of protection to the kidney. 3. The degree of protection conferred by the alkaline solution is associated with the ability of the solution to maintain a normal acid-base equilibrium of the blood of the anesthetized animal. The Rockefeller University Press 1918-10-01 /pmc/articles/PMC2126284/ /pubmed/19868273 Text en Copyright © Copyright, 1918, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article MacNider, William deB. THE STABILITY OF THE ACID-BASE EQUILIBRIUM OF THE BLOOD IN NATURALLY NEPHROPATHIC ANIMALS AND THE EFFECT ON RENAL FUNCTION OF CHANGES IN THIS EQUILIBRIUM : II. A STUDY OF THE EFFICIENCY OF AN ALKALI TO PROTECT THE NATURALLY NEPHROPATHIC KIDNEY AGAINST THE TOXIC EFFECT OF AN ANESTHETIC. |
title | THE STABILITY OF THE ACID-BASE EQUILIBRIUM OF THE BLOOD IN NATURALLY NEPHROPATHIC ANIMALS AND THE EFFECT ON RENAL FUNCTION OF CHANGES IN THIS EQUILIBRIUM : II. A STUDY OF THE EFFICIENCY OF AN ALKALI TO PROTECT THE NATURALLY NEPHROPATHIC KIDNEY AGAINST THE TOXIC EFFECT OF AN ANESTHETIC. |
title_full | THE STABILITY OF THE ACID-BASE EQUILIBRIUM OF THE BLOOD IN NATURALLY NEPHROPATHIC ANIMALS AND THE EFFECT ON RENAL FUNCTION OF CHANGES IN THIS EQUILIBRIUM : II. A STUDY OF THE EFFICIENCY OF AN ALKALI TO PROTECT THE NATURALLY NEPHROPATHIC KIDNEY AGAINST THE TOXIC EFFECT OF AN ANESTHETIC. |
title_fullStr | THE STABILITY OF THE ACID-BASE EQUILIBRIUM OF THE BLOOD IN NATURALLY NEPHROPATHIC ANIMALS AND THE EFFECT ON RENAL FUNCTION OF CHANGES IN THIS EQUILIBRIUM : II. A STUDY OF THE EFFICIENCY OF AN ALKALI TO PROTECT THE NATURALLY NEPHROPATHIC KIDNEY AGAINST THE TOXIC EFFECT OF AN ANESTHETIC. |
title_full_unstemmed | THE STABILITY OF THE ACID-BASE EQUILIBRIUM OF THE BLOOD IN NATURALLY NEPHROPATHIC ANIMALS AND THE EFFECT ON RENAL FUNCTION OF CHANGES IN THIS EQUILIBRIUM : II. A STUDY OF THE EFFICIENCY OF AN ALKALI TO PROTECT THE NATURALLY NEPHROPATHIC KIDNEY AGAINST THE TOXIC EFFECT OF AN ANESTHETIC. |
title_short | THE STABILITY OF THE ACID-BASE EQUILIBRIUM OF THE BLOOD IN NATURALLY NEPHROPATHIC ANIMALS AND THE EFFECT ON RENAL FUNCTION OF CHANGES IN THIS EQUILIBRIUM : II. A STUDY OF THE EFFICIENCY OF AN ALKALI TO PROTECT THE NATURALLY NEPHROPATHIC KIDNEY AGAINST THE TOXIC EFFECT OF AN ANESTHETIC. |
title_sort | stability of the acid-base equilibrium of the blood in naturally nephropathic animals and the effect on renal function of changes in this equilibrium : ii. a study of the efficiency of an alkali to protect the naturally nephropathic kidney against the toxic effect of an anesthetic. |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2126284/ https://www.ncbi.nlm.nih.gov/pubmed/19868273 |
work_keys_str_mv | AT macniderwilliamdeb thestabilityoftheacidbaseequilibriumofthebloodinnaturallynephropathicanimalsandtheeffectonrenalfunctionofchangesinthisequilibriumiiastudyoftheefficiencyofanalkalitoprotectthenaturallynephropathickidneyagainstthetoxiceffectofananesthetic AT macniderwilliamdeb stabilityoftheacidbaseequilibriumofthebloodinnaturallynephropathicanimalsandtheeffectonrenalfunctionofchangesinthisequilibriumiiastudyoftheefficiencyofanalkalitoprotectthenaturallynephropathickidneyagainstthetoxiceffectofananesthetic |