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A Functional Analysis of the Spacer of V(D)J Recombination Signal Sequences

During lymphocyte development, V(D)J recombination assembles antigen receptor genes from component V, D, and J gene segments. These gene segments are flanked by a recombination signal sequence (RSS), which serves as the binding site for the recombination machinery. The murine Jβ2.6 gene segment is a...

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Detalles Bibliográficos
Autores principales: Lee, Alfred Ian, Fugmann, Sebastian D, Cowell, Lindsay G, Ptaszek, Leon M, Kelsoe, Garnett, Schatz, David G
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC212687/
https://www.ncbi.nlm.nih.gov/pubmed/14551903
http://dx.doi.org/10.1371/journal.pbio.0000001