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STUDIES ON COMPLEMENT FIXATION : I. THE RATE OF FIXATION OF COMPLEMENT AT DIFFERENT TEMPERATURES.

It is shown by complement fixation studies with protein antigens and specific immune rabbit sera that the rate of fixation of complement is determined by the concentration of antibodies in the immune sera, that the greater part of fixation of complement takes place during the 1st hour, and that fixa...

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Detalles Bibliográficos
Autor principal: Kahn, R. L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1921
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2128092/
https://www.ncbi.nlm.nih.gov/pubmed/19868553
Descripción
Sumario:It is shown by complement fixation studies with protein antigens and specific immune rabbit sera that the rate of fixation of complement is determined by the concentration of antibodies in the immune sera, that the greater part of fixation of complement takes place during the 1st hour, and that fixation is practically completed at the end of 4 hours at ice box temperature. It is further shown that the rate. of fixation of complement is practically the same at ice box, room, and water bath temperatures, the tendency being for slightly stronger fixation at ice box temperature.