Cargando…

THE INFLUENCE OF THYROID PRODUCTS ON THE PRODUCTION OF MYOCARDIAL NECROSIS

An experimental study upon the demonstrable effects of large doses of dried thyroid gland and thyroxin upon the myocardium of rabbits has been made. Animals under such treatment show characteristic clinical symptoms with definite, although relatively slight, myocardial lesions. Similarly treated ani...

Descripción completa

Detalles Bibliográficos
Autor principal: Goodpasture, Ernest W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1921
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2128153/
https://www.ncbi.nlm.nih.gov/pubmed/19868566
Descripción
Sumario:An experimental study upon the demonstrable effects of large doses of dried thyroid gland and thyroxin upon the myocardium of rabbits has been made. Animals under such treatment show characteristic clinical symptoms with definite, although relatively slight, myocardial lesions. Similarly treated animals which have, in addition, been subjected to chloroform anesthesia show more striking, widespread myocardial necrosis. These experiments indicate very distinctly that chloroform as an anesthetic in cases of hyperthyroidism is apt to be exceptionally detrimental to the myocardium, and should be avoided.