THE INFLUENCE OF THYROID PRODUCTS ON THE PRODUCTION OF MYOCARDIAL NECROSIS

An experimental study upon the demonstrable effects of large doses of dried thyroid gland and thyroxin upon the myocardium of rabbits has been made. Animals under such treatment show characteristic clinical symptoms with definite, although relatively slight, myocardial lesions. Similarly treated ani...

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Detalles Bibliográficos
Autor principal: Goodpasture, Ernest W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1921
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2128153/
https://www.ncbi.nlm.nih.gov/pubmed/19868566
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author Goodpasture, Ernest W.
author_facet Goodpasture, Ernest W.
author_sort Goodpasture, Ernest W.
collection PubMed
description An experimental study upon the demonstrable effects of large doses of dried thyroid gland and thyroxin upon the myocardium of rabbits has been made. Animals under such treatment show characteristic clinical symptoms with definite, although relatively slight, myocardial lesions. Similarly treated animals which have, in addition, been subjected to chloroform anesthesia show more striking, widespread myocardial necrosis. These experiments indicate very distinctly that chloroform as an anesthetic in cases of hyperthyroidism is apt to be exceptionally detrimental to the myocardium, and should be avoided.
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spelling pubmed-21281532008-04-18 THE INFLUENCE OF THYROID PRODUCTS ON THE PRODUCTION OF MYOCARDIAL NECROSIS Goodpasture, Ernest W. J Exp Med Article An experimental study upon the demonstrable effects of large doses of dried thyroid gland and thyroxin upon the myocardium of rabbits has been made. Animals under such treatment show characteristic clinical symptoms with definite, although relatively slight, myocardial lesions. Similarly treated animals which have, in addition, been subjected to chloroform anesthesia show more striking, widespread myocardial necrosis. These experiments indicate very distinctly that chloroform as an anesthetic in cases of hyperthyroidism is apt to be exceptionally detrimental to the myocardium, and should be avoided. The Rockefeller University Press 1921-09-30 /pmc/articles/PMC2128153/ /pubmed/19868566 Text en Copyright © Copyright, 1921, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Goodpasture, Ernest W.
THE INFLUENCE OF THYROID PRODUCTS ON THE PRODUCTION OF MYOCARDIAL NECROSIS
title THE INFLUENCE OF THYROID PRODUCTS ON THE PRODUCTION OF MYOCARDIAL NECROSIS
title_full THE INFLUENCE OF THYROID PRODUCTS ON THE PRODUCTION OF MYOCARDIAL NECROSIS
title_fullStr THE INFLUENCE OF THYROID PRODUCTS ON THE PRODUCTION OF MYOCARDIAL NECROSIS
title_full_unstemmed THE INFLUENCE OF THYROID PRODUCTS ON THE PRODUCTION OF MYOCARDIAL NECROSIS
title_short THE INFLUENCE OF THYROID PRODUCTS ON THE PRODUCTION OF MYOCARDIAL NECROSIS
title_sort influence of thyroid products on the production of myocardial necrosis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2128153/
https://www.ncbi.nlm.nih.gov/pubmed/19868566
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