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CONDITION OF THE CAPILLARIES IN HISTAMINE SHOCK

1. Histamine exerts a local dilator effect upon capillaries and upon the smallest arterioles and venules which border the capillary system. There occurs also an opening up of large numbers of capillaries of which no trace can be seen before the application of histamine. 2. When injected intravenousl...

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Detalles Bibliográficos
Autor principal: Rich, Arnold Rice
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1921
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2128181/
https://www.ncbi.nlm.nih.gov/pubmed/19868496
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author Rich, Arnold Rice
author_facet Rich, Arnold Rice
author_sort Rich, Arnold Rice
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description 1. Histamine exerts a local dilator effect upon capillaries and upon the smallest arterioles and venules which border the capillary system. There occurs also an opening up of large numbers of capillaries of which no trace can be seen before the application of histamine. 2. When injected intravenously in amounts sufficient to produce shock, histamine causes a quickly progressive dilatation of both the visible and the occult capillaries and of their immediately adjacent arterioles and venules, all of which become engorged with blood that moves through them in a strikingly sluggish manner. The circulatory failure which characterizes histamine shock results from the dilatation of the peripheral vascular bed.
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spelling pubmed-21281812008-04-18 CONDITION OF THE CAPILLARIES IN HISTAMINE SHOCK Rich, Arnold Rice J Exp Med Article 1. Histamine exerts a local dilator effect upon capillaries and upon the smallest arterioles and venules which border the capillary system. There occurs also an opening up of large numbers of capillaries of which no trace can be seen before the application of histamine. 2. When injected intravenously in amounts sufficient to produce shock, histamine causes a quickly progressive dilatation of both the visible and the occult capillaries and of their immediately adjacent arterioles and venules, all of which become engorged with blood that moves through them in a strikingly sluggish manner. The circulatory failure which characterizes histamine shock results from the dilatation of the peripheral vascular bed. The Rockefeller University Press 1921-01-31 /pmc/articles/PMC2128181/ /pubmed/19868496 Text en Copyright © Copyright, 1921, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Rich, Arnold Rice
CONDITION OF THE CAPILLARIES IN HISTAMINE SHOCK
title CONDITION OF THE CAPILLARIES IN HISTAMINE SHOCK
title_full CONDITION OF THE CAPILLARIES IN HISTAMINE SHOCK
title_fullStr CONDITION OF THE CAPILLARIES IN HISTAMINE SHOCK
title_full_unstemmed CONDITION OF THE CAPILLARIES IN HISTAMINE SHOCK
title_short CONDITION OF THE CAPILLARIES IN HISTAMINE SHOCK
title_sort condition of the capillaries in histamine shock
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2128181/
https://www.ncbi.nlm.nih.gov/pubmed/19868496
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