PURE CULTURES OF LARGE MONONUCLEAR LEUCOCYTES

1. Pure strains of mononuclear leucocytes were isolated from the blood of adult chickens and keptin active condition for nearly 3 months. 2. The cultures were composed of large mononuclear leucocytes which migrated and proliferated in vitro at a slower rate than fibroblasts. The cells had no tendenc...

Descripción completa

Detalles Bibliográficos
Autores principales: Carrel, Alexis, Ebeling, Albert H.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1922
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2128308/
https://www.ncbi.nlm.nih.gov/pubmed/19868678
_version_ 1782142040360878080
author Carrel, Alexis
Ebeling, Albert H.
author_facet Carrel, Alexis
Ebeling, Albert H.
author_sort Carrel, Alexis
collection PubMed
description 1. Pure strains of mononuclear leucocytes were isolated from the blood of adult chickens and keptin active condition for nearly 3 months. 2. The cultures were composed of large mononuclear leucocytes which migrated and proliferated in vitro at a slower rate than fibroblasts. The cells had no tendency to form a tissue, as do fibroblasts and epithelial cells. They were much less resistant than fibroblasts. 3. Differentiation of the large mononuclears into cells assuming the appearance of fibroblasts took place under certain conditions. 4. The activity of the large mononuclears was increased by embryonic tissue juice and inhibited by homologous serum.
format Text
id pubmed-2128308
institution National Center for Biotechnology Information
language English
publishDate 1922
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21283082008-04-18 PURE CULTURES OF LARGE MONONUCLEAR LEUCOCYTES Carrel, Alexis Ebeling, Albert H. J Exp Med Article 1. Pure strains of mononuclear leucocytes were isolated from the blood of adult chickens and keptin active condition for nearly 3 months. 2. The cultures were composed of large mononuclear leucocytes which migrated and proliferated in vitro at a slower rate than fibroblasts. The cells had no tendency to form a tissue, as do fibroblasts and epithelial cells. They were much less resistant than fibroblasts. 3. Differentiation of the large mononuclears into cells assuming the appearance of fibroblasts took place under certain conditions. 4. The activity of the large mononuclears was increased by embryonic tissue juice and inhibited by homologous serum. The Rockefeller University Press 1922-09-30 /pmc/articles/PMC2128308/ /pubmed/19868678 Text en Copyright © Copyright, 1922, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Carrel, Alexis
Ebeling, Albert H.
PURE CULTURES OF LARGE MONONUCLEAR LEUCOCYTES
title PURE CULTURES OF LARGE MONONUCLEAR LEUCOCYTES
title_full PURE CULTURES OF LARGE MONONUCLEAR LEUCOCYTES
title_fullStr PURE CULTURES OF LARGE MONONUCLEAR LEUCOCYTES
title_full_unstemmed PURE CULTURES OF LARGE MONONUCLEAR LEUCOCYTES
title_short PURE CULTURES OF LARGE MONONUCLEAR LEUCOCYTES
title_sort pure cultures of large mononuclear leucocytes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2128308/
https://www.ncbi.nlm.nih.gov/pubmed/19868678
work_keys_str_mv AT carrelalexis pureculturesoflargemononuclearleucocytes
AT ebelingalberth pureculturesoflargemononuclearleucocytes

Ejemplares similares