STUDIES ON THE ENZYMES OF PNEUMOCOCCUS : IV. BACTERIOLYTIC ENZYME.

1. Pneumococci possess an active intracellular enzyme which causes lysis of heat-killed pneumococci of the same and heterologous types and to a less degree of a closely related organism, Streptococcus viridans. 2. The optimum reaction for lysis lies between pH 6 and 8. 3. The bacteriolytic action is...

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Detalles Bibliográficos
Autores principales: Avery, O. T., Cullen, Glenn E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1923
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2128432/
https://www.ncbi.nlm.nih.gov/pubmed/19868783
Descripción
Sumario:1. Pneumococci possess an active intracellular enzyme which causes lysis of heat-killed pneumococci of the same and heterologous types and to a less degree of a closely related organism, Streptococcus viridans. 2. The optimum reaction for lysis lies between pH 6 and 8. 3. The bacteriolytic action is proportional to the concentration of the enzyme. 4. Heating the enzyme for 30 minutes at 60°C. destroys its activity. 5. The possible relation of the enzyme to autolysis is discussed.

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