STUDIES ON THE ENZYMES OF PNEUMOCOCCUS : IV. BACTERIOLYTIC ENZYME.

1. Pneumococci possess an active intracellular enzyme which causes lysis of heat-killed pneumococci of the same and heterologous types and to a less degree of a closely related organism, Streptococcus viridans. 2. The optimum reaction for lysis lies between pH 6 and 8. 3. The bacteriolytic action is...

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Detalles Bibliográficos
Autores principales: Avery, O. T., Cullen, Glenn E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1923
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2128432/
https://www.ncbi.nlm.nih.gov/pubmed/19868783
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author Avery, O. T.
Cullen, Glenn E.
author_facet Avery, O. T.
Cullen, Glenn E.
author_sort Avery, O. T.
collection PubMed
description 1. Pneumococci possess an active intracellular enzyme which causes lysis of heat-killed pneumococci of the same and heterologous types and to a less degree of a closely related organism, Streptococcus viridans. 2. The optimum reaction for lysis lies between pH 6 and 8. 3. The bacteriolytic action is proportional to the concentration of the enzyme. 4. Heating the enzyme for 30 minutes at 60°C. destroys its activity. 5. The possible relation of the enzyme to autolysis is discussed.
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spelling pubmed-21284322008-04-18 STUDIES ON THE ENZYMES OF PNEUMOCOCCUS : IV. BACTERIOLYTIC ENZYME. Avery, O. T. Cullen, Glenn E. J Exp Med Article 1. Pneumococci possess an active intracellular enzyme which causes lysis of heat-killed pneumococci of the same and heterologous types and to a less degree of a closely related organism, Streptococcus viridans. 2. The optimum reaction for lysis lies between pH 6 and 8. 3. The bacteriolytic action is proportional to the concentration of the enzyme. 4. Heating the enzyme for 30 minutes at 60°C. destroys its activity. 5. The possible relation of the enzyme to autolysis is discussed. The Rockefeller University Press 1923-07-31 /pmc/articles/PMC2128432/ /pubmed/19868783 Text en Copyright © Copyright, 1923, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Avery, O. T.
Cullen, Glenn E.
STUDIES ON THE ENZYMES OF PNEUMOCOCCUS : IV. BACTERIOLYTIC ENZYME.
title STUDIES ON THE ENZYMES OF PNEUMOCOCCUS : IV. BACTERIOLYTIC ENZYME.
title_full STUDIES ON THE ENZYMES OF PNEUMOCOCCUS : IV. BACTERIOLYTIC ENZYME.
title_fullStr STUDIES ON THE ENZYMES OF PNEUMOCOCCUS : IV. BACTERIOLYTIC ENZYME.
title_full_unstemmed STUDIES ON THE ENZYMES OF PNEUMOCOCCUS : IV. BACTERIOLYTIC ENZYME.
title_short STUDIES ON THE ENZYMES OF PNEUMOCOCCUS : IV. BACTERIOLYTIC ENZYME.
title_sort studies on the enzymes of pneumococcus : iv. bacteriolytic enzyme.
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2128432/
https://www.ncbi.nlm.nih.gov/pubmed/19868783
work_keys_str_mv AT averyot studiesontheenzymesofpneumococcusivbacteriolyticenzyme
AT cullenglenne studiesontheenzymesofpneumococcusivbacteriolyticenzyme

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