A REACTION PRODUCT IN INFECTIONS WITH TRYPANOSOMA LEWISI WHICH INHIBITS THE REPRODUCTION OF THE TRYPANOSOMES

1. In infections with Trypanosoma lewisi in the rat there are three manifestations of resistance against the parasite: (1) the retardation and final inhibition of reproduction of the trypanosomes by about the 10th day; (2) a sudden drop in the number of parasites in the blood between the 9th and 15t...

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Autor principal: Taliaferro, William H.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1924
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2128466/
https://www.ncbi.nlm.nih.gov/pubmed/19868831
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author Taliaferro, William H.
author_facet Taliaferro, William H.
author_sort Taliaferro, William H.
collection PubMed
description 1. In infections with Trypanosoma lewisi in the rat there are three manifestations of resistance against the parasite: (1) the retardation and final inhibition of reproduction of the trypanosomes by about the 10th day; (2) a sudden drop in the number of parasites in the blood between the 9th and 15th days; and (3) the total disappearance of the parasites, which terminates the infection and occurs from a week to several months after the first drop in numbers. 2. The first manifestation of resistance, vis. the retardation and final inhibition of reproduction, is the result of the formation of a reaction product in infected rats which inhibits reproduction of the trypanosomes but does not kill them. 3. No product similar to, or identical with this reaction product can be demonstrated in in vitro cultures of Trypanosoma lewisi.
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spelling pubmed-21284662008-04-18 A REACTION PRODUCT IN INFECTIONS WITH TRYPANOSOMA LEWISI WHICH INHIBITS THE REPRODUCTION OF THE TRYPANOSOMES Taliaferro, William H. J Exp Med Article 1. In infections with Trypanosoma lewisi in the rat there are three manifestations of resistance against the parasite: (1) the retardation and final inhibition of reproduction of the trypanosomes by about the 10th day; (2) a sudden drop in the number of parasites in the blood between the 9th and 15th days; and (3) the total disappearance of the parasites, which terminates the infection and occurs from a week to several months after the first drop in numbers. 2. The first manifestation of resistance, vis. the retardation and final inhibition of reproduction, is the result of the formation of a reaction product in infected rats which inhibits reproduction of the trypanosomes but does not kill them. 3. No product similar to, or identical with this reaction product can be demonstrated in in vitro cultures of Trypanosoma lewisi. The Rockefeller University Press 1924-01-01 /pmc/articles/PMC2128466/ /pubmed/19868831 Text en Copyright © Copyright, 1924, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Taliaferro, William H.
A REACTION PRODUCT IN INFECTIONS WITH TRYPANOSOMA LEWISI WHICH INHIBITS THE REPRODUCTION OF THE TRYPANOSOMES
title A REACTION PRODUCT IN INFECTIONS WITH TRYPANOSOMA LEWISI WHICH INHIBITS THE REPRODUCTION OF THE TRYPANOSOMES
title_full A REACTION PRODUCT IN INFECTIONS WITH TRYPANOSOMA LEWISI WHICH INHIBITS THE REPRODUCTION OF THE TRYPANOSOMES
title_fullStr A REACTION PRODUCT IN INFECTIONS WITH TRYPANOSOMA LEWISI WHICH INHIBITS THE REPRODUCTION OF THE TRYPANOSOMES
title_full_unstemmed A REACTION PRODUCT IN INFECTIONS WITH TRYPANOSOMA LEWISI WHICH INHIBITS THE REPRODUCTION OF THE TRYPANOSOMES
title_short A REACTION PRODUCT IN INFECTIONS WITH TRYPANOSOMA LEWISI WHICH INHIBITS THE REPRODUCTION OF THE TRYPANOSOMES
title_sort reaction product in infections with trypanosoma lewisi which inhibits the reproduction of the trypanosomes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2128466/
https://www.ncbi.nlm.nih.gov/pubmed/19868831
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