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ON THE ANTIGENIC PROPERTIES OF HEMOGLOBIN
Sera produced by immunization with crystalline oxyhemoglobin react species-specifically with hemoglobin solutions. Evidence is presented that in this reaction the hemoglobin itself is the active substance. Conversion of oxyhemoglobin into methemoglobin, carbon-monoxy hemoglobin, or cyanhemoglobin do...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1923
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2128479/ https://www.ncbi.nlm.nih.gov/pubmed/19868810 |
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author | Heidelberger, M. Landsteiner, K. |
author_facet | Heidelberger, M. Landsteiner, K. |
author_sort | Heidelberger, M. |
collection | PubMed |
description | Sera produced by immunization with crystalline oxyhemoglobin react species-specifically with hemoglobin solutions. Evidence is presented that in this reaction the hemoglobin itself is the active substance. Conversion of oxyhemoglobin into methemoglobin, carbon-monoxy hemoglobin, or cyanhemoglobin does not alter the response to the precipitating immune serum. Not only the hemoglobin of homologous species, but also that of other species causes inhibition in greater or less degree of the precipitin reaction. |
format | Text |
id | pubmed-2128479 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1923 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21284792008-04-18 ON THE ANTIGENIC PROPERTIES OF HEMOGLOBIN Heidelberger, M. Landsteiner, K. J Exp Med Article Sera produced by immunization with crystalline oxyhemoglobin react species-specifically with hemoglobin solutions. Evidence is presented that in this reaction the hemoglobin itself is the active substance. Conversion of oxyhemoglobin into methemoglobin, carbon-monoxy hemoglobin, or cyanhemoglobin does not alter the response to the precipitating immune serum. Not only the hemoglobin of homologous species, but also that of other species causes inhibition in greater or less degree of the precipitin reaction. The Rockefeller University Press 1923-10-31 /pmc/articles/PMC2128479/ /pubmed/19868810 Text en Copyright © Copyright, 1923, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Heidelberger, M. Landsteiner, K. ON THE ANTIGENIC PROPERTIES OF HEMOGLOBIN |
title | ON THE ANTIGENIC PROPERTIES OF HEMOGLOBIN |
title_full | ON THE ANTIGENIC PROPERTIES OF HEMOGLOBIN |
title_fullStr | ON THE ANTIGENIC PROPERTIES OF HEMOGLOBIN |
title_full_unstemmed | ON THE ANTIGENIC PROPERTIES OF HEMOGLOBIN |
title_short | ON THE ANTIGENIC PROPERTIES OF HEMOGLOBIN |
title_sort | on the antigenic properties of hemoglobin |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2128479/ https://www.ncbi.nlm.nih.gov/pubmed/19868810 |
work_keys_str_mv | AT heidelbergerm ontheantigenicpropertiesofhemoglobin AT landsteinerk ontheantigenicpropertiesofhemoglobin |