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ON THE ANTIGENIC PROPERTIES OF HEMOGLOBIN

Sera produced by immunization with crystalline oxyhemoglobin react species-specifically with hemoglobin solutions. Evidence is presented that in this reaction the hemoglobin itself is the active substance. Conversion of oxyhemoglobin into methemoglobin, carbon-monoxy hemoglobin, or cyanhemoglobin do...

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Detalles Bibliográficos
Autores principales: Heidelberger, M., Landsteiner, K.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1923
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2128479/
https://www.ncbi.nlm.nih.gov/pubmed/19868810
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author Heidelberger, M.
Landsteiner, K.
author_facet Heidelberger, M.
Landsteiner, K.
author_sort Heidelberger, M.
collection PubMed
description Sera produced by immunization with crystalline oxyhemoglobin react species-specifically with hemoglobin solutions. Evidence is presented that in this reaction the hemoglobin itself is the active substance. Conversion of oxyhemoglobin into methemoglobin, carbon-monoxy hemoglobin, or cyanhemoglobin does not alter the response to the precipitating immune serum. Not only the hemoglobin of homologous species, but also that of other species causes inhibition in greater or less degree of the precipitin reaction.
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spelling pubmed-21284792008-04-18 ON THE ANTIGENIC PROPERTIES OF HEMOGLOBIN Heidelberger, M. Landsteiner, K. J Exp Med Article Sera produced by immunization with crystalline oxyhemoglobin react species-specifically with hemoglobin solutions. Evidence is presented that in this reaction the hemoglobin itself is the active substance. Conversion of oxyhemoglobin into methemoglobin, carbon-monoxy hemoglobin, or cyanhemoglobin does not alter the response to the precipitating immune serum. Not only the hemoglobin of homologous species, but also that of other species causes inhibition in greater or less degree of the precipitin reaction. The Rockefeller University Press 1923-10-31 /pmc/articles/PMC2128479/ /pubmed/19868810 Text en Copyright © Copyright, 1923, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Heidelberger, M.
Landsteiner, K.
ON THE ANTIGENIC PROPERTIES OF HEMOGLOBIN
title ON THE ANTIGENIC PROPERTIES OF HEMOGLOBIN
title_full ON THE ANTIGENIC PROPERTIES OF HEMOGLOBIN
title_fullStr ON THE ANTIGENIC PROPERTIES OF HEMOGLOBIN
title_full_unstemmed ON THE ANTIGENIC PROPERTIES OF HEMOGLOBIN
title_short ON THE ANTIGENIC PROPERTIES OF HEMOGLOBIN
title_sort on the antigenic properties of hemoglobin
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2128479/
https://www.ncbi.nlm.nih.gov/pubmed/19868810
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