AN IMMUNIZING STRAIN OF THE VIRUS OF POLIOMYELITIS

In this communication we have described a strain of the virus of poliomyelitis derived from a rapidly fatal human case, which exhibits mild degrees of infective power and marked degrees of protective effect for the monkey. While Macacus rhesus displays perceptible differences in suceptibility to the...

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Detalles Bibliográficos
Autores principales: Flexner, Simon, Amoss, Harold L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1924
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2128531/
https://www.ncbi.nlm.nih.gov/pubmed/19868872
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author Flexner, Simon
Amoss, Harold L.
author_facet Flexner, Simon
Amoss, Harold L.
author_sort Flexner, Simon
collection PubMed
description In this communication we have described a strain of the virus of poliomyelitis derived from a rapidly fatal human case, which exhibits mild degrees of infective power and marked degrees of protective effect for the monkey. While Macacus rhesus displays perceptible differences in suceptibility to the attenuated virus, nearly all individuals respond to the inoculation and none succumbs to the infection induced. As compared with previously described examples of experimental poliomyelitis, the modified disease described in this paper is distinguished by its relatively benign nature and its tendency to end in recovery rather than, as with the earlier observed instances, in death.
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spelling pubmed-21285312008-04-18 AN IMMUNIZING STRAIN OF THE VIRUS OF POLIOMYELITIS Flexner, Simon Amoss, Harold L. J Exp Med Article In this communication we have described a strain of the virus of poliomyelitis derived from a rapidly fatal human case, which exhibits mild degrees of infective power and marked degrees of protective effect for the monkey. While Macacus rhesus displays perceptible differences in suceptibility to the attenuated virus, nearly all individuals respond to the inoculation and none succumbs to the infection induced. As compared with previously described examples of experimental poliomyelitis, the modified disease described in this paper is distinguished by its relatively benign nature and its tendency to end in recovery rather than, as with the earlier observed instances, in death. The Rockefeller University Press 1924-04-30 /pmc/articles/PMC2128531/ /pubmed/19868872 Text en Copyright © Copyright, 1924, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Flexner, Simon
Amoss, Harold L.
AN IMMUNIZING STRAIN OF THE VIRUS OF POLIOMYELITIS
title AN IMMUNIZING STRAIN OF THE VIRUS OF POLIOMYELITIS
title_full AN IMMUNIZING STRAIN OF THE VIRUS OF POLIOMYELITIS
title_fullStr AN IMMUNIZING STRAIN OF THE VIRUS OF POLIOMYELITIS
title_full_unstemmed AN IMMUNIZING STRAIN OF THE VIRUS OF POLIOMYELITIS
title_short AN IMMUNIZING STRAIN OF THE VIRUS OF POLIOMYELITIS
title_sort immunizing strain of the virus of poliomyelitis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2128531/
https://www.ncbi.nlm.nih.gov/pubmed/19868872
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