THE FATE OF ANTIGEN (PROTEIN) IN AN ANIMAL IMMUNIZED AGAINST IT

When proteins such as horse serum or crystalline egg albumin which have been selected because they produce the phenomena of immunity are introduced into a normal animal they diffuse widely in the tissue, enter the blood stream, and are disseminated throughout the body. The same substances introduced...

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Detalles Bibliográficos
Autor principal: Opie, Eugene L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1924
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2128535/
https://www.ncbi.nlm.nih.gov/pubmed/19868876
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author Opie, Eugene L.
author_facet Opie, Eugene L.
author_sort Opie, Eugene L.
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description When proteins such as horse serum or crystalline egg albumin which have been selected because they produce the phenomena of immunity are introduced into a normal animal they diffuse widely in the tissue, enter the blood stream, and are disseminated throughout the body. The same substances introduced into an immune animal are fixed at the site of entry and are not found in the blood. When protein is injected into the skin of an immune animal acute inflammation (Arthus phenomenon) occurs at the site of injection and brings about destruction of the foreign substance.
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spelling pubmed-21285352008-04-18 THE FATE OF ANTIGEN (PROTEIN) IN AN ANIMAL IMMUNIZED AGAINST IT Opie, Eugene L. J Exp Med Article When proteins such as horse serum or crystalline egg albumin which have been selected because they produce the phenomena of immunity are introduced into a normal animal they diffuse widely in the tissue, enter the blood stream, and are disseminated throughout the body. The same substances introduced into an immune animal are fixed at the site of entry and are not found in the blood. When protein is injected into the skin of an immune animal acute inflammation (Arthus phenomenon) occurs at the site of injection and brings about destruction of the foreign substance. The Rockefeller University Press 1924-04-30 /pmc/articles/PMC2128535/ /pubmed/19868876 Text en Copyright © Copyright, 1924, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Opie, Eugene L.
THE FATE OF ANTIGEN (PROTEIN) IN AN ANIMAL IMMUNIZED AGAINST IT
title THE FATE OF ANTIGEN (PROTEIN) IN AN ANIMAL IMMUNIZED AGAINST IT
title_full THE FATE OF ANTIGEN (PROTEIN) IN AN ANIMAL IMMUNIZED AGAINST IT
title_fullStr THE FATE OF ANTIGEN (PROTEIN) IN AN ANIMAL IMMUNIZED AGAINST IT
title_full_unstemmed THE FATE OF ANTIGEN (PROTEIN) IN AN ANIMAL IMMUNIZED AGAINST IT
title_short THE FATE OF ANTIGEN (PROTEIN) IN AN ANIMAL IMMUNIZED AGAINST IT
title_sort fate of antigen (protein) in an animal immunized against it
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2128535/
https://www.ncbi.nlm.nih.gov/pubmed/19868876
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