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STUDIES ON OXIDATION AND REDUCTION BY PNEUMOCOCCUS : VII. ENZYME ACTIVITY OF STERILE FILTRATES OF AEROBIC AND ANAEROBIC CULTURES OF PNEUMOCOCCUS.
Sterile filtrates of autolyzed anaerobic cultures of Pneumococcus contain much higher concentrations of active endocellular enzymes than do the filtrates of autolyzed aerobic cultures. These differences in the enzyme activity of the filtrates of aerobic and anaerobic cultures may be explained by a d...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1924
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2128591/ https://www.ncbi.nlm.nih.gov/pubmed/19868929 |
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author | Neill, James M. Avery, Oswald T. |
author_facet | Neill, James M. Avery, Oswald T. |
author_sort | Neill, James M. |
collection | PubMed |
description | Sterile filtrates of autolyzed anaerobic cultures of Pneumococcus contain much higher concentrations of active endocellular enzymes than do the filtrates of autolyzed aerobic cultures. These differences in the enzyme activity of the filtrates of aerobic and anaerobic cultures may be explained by a destruction of the formed enzymes by oxidation reactions analogous to the destruction previously observed during the oxidation of sterile broth extracts of unwashed pneumococcus cells. The occurrence of more complete destruction of enzyme activity in autolyzed aerobic cultures than in "oxidized" sterile cell extracts is probably due to the longer exposure to oxidation products. |
format | Text |
id | pubmed-2128591 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1924 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21285912008-04-18 STUDIES ON OXIDATION AND REDUCTION BY PNEUMOCOCCUS : VII. ENZYME ACTIVITY OF STERILE FILTRATES OF AEROBIC AND ANAEROBIC CULTURES OF PNEUMOCOCCUS. Neill, James M. Avery, Oswald T. J Exp Med Article Sterile filtrates of autolyzed anaerobic cultures of Pneumococcus contain much higher concentrations of active endocellular enzymes than do the filtrates of autolyzed aerobic cultures. These differences in the enzyme activity of the filtrates of aerobic and anaerobic cultures may be explained by a destruction of the formed enzymes by oxidation reactions analogous to the destruction previously observed during the oxidation of sterile broth extracts of unwashed pneumococcus cells. The occurrence of more complete destruction of enzyme activity in autolyzed aerobic cultures than in "oxidized" sterile cell extracts is probably due to the longer exposure to oxidation products. The Rockefeller University Press 1924-09-30 /pmc/articles/PMC2128591/ /pubmed/19868929 Text en Copyright © Copyright, 1924, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Neill, James M. Avery, Oswald T. STUDIES ON OXIDATION AND REDUCTION BY PNEUMOCOCCUS : VII. ENZYME ACTIVITY OF STERILE FILTRATES OF AEROBIC AND ANAEROBIC CULTURES OF PNEUMOCOCCUS. |
title | STUDIES ON OXIDATION AND REDUCTION BY PNEUMOCOCCUS : VII. ENZYME ACTIVITY OF STERILE FILTRATES OF AEROBIC AND ANAEROBIC CULTURES OF PNEUMOCOCCUS. |
title_full | STUDIES ON OXIDATION AND REDUCTION BY PNEUMOCOCCUS : VII. ENZYME ACTIVITY OF STERILE FILTRATES OF AEROBIC AND ANAEROBIC CULTURES OF PNEUMOCOCCUS. |
title_fullStr | STUDIES ON OXIDATION AND REDUCTION BY PNEUMOCOCCUS : VII. ENZYME ACTIVITY OF STERILE FILTRATES OF AEROBIC AND ANAEROBIC CULTURES OF PNEUMOCOCCUS. |
title_full_unstemmed | STUDIES ON OXIDATION AND REDUCTION BY PNEUMOCOCCUS : VII. ENZYME ACTIVITY OF STERILE FILTRATES OF AEROBIC AND ANAEROBIC CULTURES OF PNEUMOCOCCUS. |
title_short | STUDIES ON OXIDATION AND REDUCTION BY PNEUMOCOCCUS : VII. ENZYME ACTIVITY OF STERILE FILTRATES OF AEROBIC AND ANAEROBIC CULTURES OF PNEUMOCOCCUS. |
title_sort | studies on oxidation and reduction by pneumococcus : vii. enzyme activity of sterile filtrates of aerobic and anaerobic cultures of pneumococcus. |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2128591/ https://www.ncbi.nlm.nih.gov/pubmed/19868929 |
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