EFFECT OF PREPUBERTY CASTRATION ON SUBSEQUENT CANCER IMPLANTATION

Male and female mice castrated during the first 7 weeks of life and implanted with cancer at later periods show a resistance definitely higher than do intact animals of the same age. This increased refractiveness is evident at 3 months after the operation but is more pronounced at 8 months to a year...

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Detalles Bibliográficos
Autores principales: Murphy, James B., Sturm, Ernest
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1925
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131001/
https://www.ncbi.nlm.nih.gov/pubmed/19869042
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author Murphy, James B.
Sturm, Ernest
author_facet Murphy, James B.
Sturm, Ernest
author_sort Murphy, James B.
collection PubMed
description Male and female mice castrated during the first 7 weeks of life and implanted with cancer at later periods show a resistance definitely higher than do intact animals of the same age. This increased refractiveness is evident at 3 months after the operation but is more pronounced at 8 months to a year. Even castration in early adult life seems to increase the refractory state to later cancer inoculation. On the other hand, adult mice inoculated within a week after castration show slight if any evidence of increased resistance.
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spelling pubmed-21310012008-04-18 EFFECT OF PREPUBERTY CASTRATION ON SUBSEQUENT CANCER IMPLANTATION Murphy, James B. Sturm, Ernest J Exp Med Article Male and female mice castrated during the first 7 weeks of life and implanted with cancer at later periods show a resistance definitely higher than do intact animals of the same age. This increased refractiveness is evident at 3 months after the operation but is more pronounced at 8 months to a year. Even castration in early adult life seems to increase the refractory state to later cancer inoculation. On the other hand, adult mice inoculated within a week after castration show slight if any evidence of increased resistance. The Rockefeller University Press 1925-07-31 /pmc/articles/PMC2131001/ /pubmed/19869042 Text en Copyright © Copyright, 1925, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Murphy, James B.
Sturm, Ernest
EFFECT OF PREPUBERTY CASTRATION ON SUBSEQUENT CANCER IMPLANTATION
title EFFECT OF PREPUBERTY CASTRATION ON SUBSEQUENT CANCER IMPLANTATION
title_full EFFECT OF PREPUBERTY CASTRATION ON SUBSEQUENT CANCER IMPLANTATION
title_fullStr EFFECT OF PREPUBERTY CASTRATION ON SUBSEQUENT CANCER IMPLANTATION
title_full_unstemmed EFFECT OF PREPUBERTY CASTRATION ON SUBSEQUENT CANCER IMPLANTATION
title_short EFFECT OF PREPUBERTY CASTRATION ON SUBSEQUENT CANCER IMPLANTATION
title_sort effect of prepuberty castration on subsequent cancer implantation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131001/
https://www.ncbi.nlm.nih.gov/pubmed/19869042
work_keys_str_mv AT murphyjamesb effectofprepubertycastrationonsubsequentcancerimplantation
AT sturmernest effectofprepubertycastrationonsubsequentcancerimplantation

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