Cargando…

EXPERIMENTAL STUDIES WITH A SPIRAL ORGANISM FOUND IN A WILD RAT AND IDENTICAL WITH THE ORGANISM CAUSING RAT-BITE FEVER : SECOND PAPER.

1. The spiral organism isolated from a wild rat has proved identical with that from a human case of rat-bite fever in Mexico City. 2. Rabbits can easily be infected with these organisms. 3. The subcutaneous inoculation of them is followed after 3 to 5 days by a local edema, induration, and inflammat...

Descripción completa

Detalles Bibliográficos
Autor principal: Mooser, H.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1925
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131026/
https://www.ncbi.nlm.nih.gov/pubmed/19869073
_version_ 1782142153440362496
author Mooser, H.
author_facet Mooser, H.
author_sort Mooser, H.
collection PubMed
description 1. The spiral organism isolated from a wild rat has proved identical with that from a human case of rat-bite fever in Mexico City. 2. Rabbits can easily be infected with these organisms. 3. The subcutaneous inoculation of them is followed after 3 to 5 days by a local edema, induration, and inflammation: primary lesion. 4. About 8 days after the appearance of the primary lesion, edematous swellings and inflammation appear on the head and genitals: secondary lesions. 5. The organism can be transmitted from rabbit to rabbit by coitus. 6. Protective antibodies are to be found in the blood of infected rabbits at a time when the local lesions are still active. The peculiar character of certain of the lesions is probably due to the escape of the antibodies from the blood stream. 7. The organism belongs to the genus Treponema.
format Text
id pubmed-2131026
institution National Center for Biotechnology Information
language English
publishDate 1925
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21310262008-04-18 EXPERIMENTAL STUDIES WITH A SPIRAL ORGANISM FOUND IN A WILD RAT AND IDENTICAL WITH THE ORGANISM CAUSING RAT-BITE FEVER : SECOND PAPER. Mooser, H. J Exp Med Article 1. The spiral organism isolated from a wild rat has proved identical with that from a human case of rat-bite fever in Mexico City. 2. Rabbits can easily be infected with these organisms. 3. The subcutaneous inoculation of them is followed after 3 to 5 days by a local edema, induration, and inflammation: primary lesion. 4. About 8 days after the appearance of the primary lesion, edematous swellings and inflammation appear on the head and genitals: secondary lesions. 5. The organism can be transmitted from rabbit to rabbit by coitus. 6. Protective antibodies are to be found in the blood of infected rabbits at a time when the local lesions are still active. The peculiar character of certain of the lesions is probably due to the escape of the antibodies from the blood stream. 7. The organism belongs to the genus Treponema. The Rockefeller University Press 1925-09-30 /pmc/articles/PMC2131026/ /pubmed/19869073 Text en Copyright © Copyright, 1925, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Mooser, H.
EXPERIMENTAL STUDIES WITH A SPIRAL ORGANISM FOUND IN A WILD RAT AND IDENTICAL WITH THE ORGANISM CAUSING RAT-BITE FEVER : SECOND PAPER.
title EXPERIMENTAL STUDIES WITH A SPIRAL ORGANISM FOUND IN A WILD RAT AND IDENTICAL WITH THE ORGANISM CAUSING RAT-BITE FEVER : SECOND PAPER.
title_full EXPERIMENTAL STUDIES WITH A SPIRAL ORGANISM FOUND IN A WILD RAT AND IDENTICAL WITH THE ORGANISM CAUSING RAT-BITE FEVER : SECOND PAPER.
title_fullStr EXPERIMENTAL STUDIES WITH A SPIRAL ORGANISM FOUND IN A WILD RAT AND IDENTICAL WITH THE ORGANISM CAUSING RAT-BITE FEVER : SECOND PAPER.
title_full_unstemmed EXPERIMENTAL STUDIES WITH A SPIRAL ORGANISM FOUND IN A WILD RAT AND IDENTICAL WITH THE ORGANISM CAUSING RAT-BITE FEVER : SECOND PAPER.
title_short EXPERIMENTAL STUDIES WITH A SPIRAL ORGANISM FOUND IN A WILD RAT AND IDENTICAL WITH THE ORGANISM CAUSING RAT-BITE FEVER : SECOND PAPER.
title_sort experimental studies with a spiral organism found in a wild rat and identical with the organism causing rat-bite fever : second paper.
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131026/
https://www.ncbi.nlm.nih.gov/pubmed/19869073
work_keys_str_mv AT mooserh experimentalstudieswithaspiralorganismfoundinawildratandidenticalwiththeorganismcausingratbitefeversecondpaper