THE SOLUBLE SPECIFIC SUBSTANCE OF PNEUMOCOCCUS : THIRD PAPER.

1. Refinements in the methods for the isolation of the soluble specific substances of Types II and III pneumococcus are described. These improvements have resulted in the isolation of the end-products in a form free from nitrogen and of enhanced activity with immune serum. 2. The soluble specific su...

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Detalles Bibliográficos
Autores principales: Heidelberger, Michael, Goebel, Walther F., Avery, Oswald T.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1925
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131056/
https://www.ncbi.nlm.nih.gov/pubmed/19869085
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author Heidelberger, Michael
Goebel, Walther F.
Avery, Oswald T.
author_facet Heidelberger, Michael
Goebel, Walther F.
Avery, Oswald T.
author_sort Heidelberger, Michael
collection PubMed
description 1. Refinements in the methods for the isolation of the soluble specific substances of Types II and III pneumococcus are described. These improvements have resulted in the isolation of the end-products in a form free from nitrogen and of enhanced activity with immune serum. 2. The soluble specific substance of Type I pneumococcus is described and shown to differ sharply from the corresponding substances of the other two types, each of which, in turn, differs from the other. 3. Progress is reported on the identification of the sugar units from which the polysaccharides are built up. 4. The evidence so far accumulated is believed to favor strongly the view that the polysaccharides isolated are the actual specific substances of Pneumococcus.
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spelling pubmed-21310562008-04-18 THE SOLUBLE SPECIFIC SUBSTANCE OF PNEUMOCOCCUS : THIRD PAPER. Heidelberger, Michael Goebel, Walther F. Avery, Oswald T. J Exp Med Article 1. Refinements in the methods for the isolation of the soluble specific substances of Types II and III pneumococcus are described. These improvements have resulted in the isolation of the end-products in a form free from nitrogen and of enhanced activity with immune serum. 2. The soluble specific substance of Type I pneumococcus is described and shown to differ sharply from the corresponding substances of the other two types, each of which, in turn, differs from the other. 3. Progress is reported on the identification of the sugar units from which the polysaccharides are built up. 4. The evidence so far accumulated is believed to favor strongly the view that the polysaccharides isolated are the actual specific substances of Pneumococcus. The Rockefeller University Press 1925-10-31 /pmc/articles/PMC2131056/ /pubmed/19869085 Text en Copyright © Copyright, 1925, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Heidelberger, Michael
Goebel, Walther F.
Avery, Oswald T.
THE SOLUBLE SPECIFIC SUBSTANCE OF PNEUMOCOCCUS : THIRD PAPER.
title THE SOLUBLE SPECIFIC SUBSTANCE OF PNEUMOCOCCUS : THIRD PAPER.
title_full THE SOLUBLE SPECIFIC SUBSTANCE OF PNEUMOCOCCUS : THIRD PAPER.
title_fullStr THE SOLUBLE SPECIFIC SUBSTANCE OF PNEUMOCOCCUS : THIRD PAPER.
title_full_unstemmed THE SOLUBLE SPECIFIC SUBSTANCE OF PNEUMOCOCCUS : THIRD PAPER.
title_short THE SOLUBLE SPECIFIC SUBSTANCE OF PNEUMOCOCCUS : THIRD PAPER.
title_sort soluble specific substance of pneumococcus : third paper.
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131056/
https://www.ncbi.nlm.nih.gov/pubmed/19869085
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