THE CULTIVATION OF THE GRANULES OF VACCINIA VIRUS

The technique is described whereby vaccinia "granules" are separated from all other material of glycerolated vaccinia calf lymph and cultivated in vitro with embryonic tissues. These "granules"remain alive, as tested by rabbit corneal inoculation, for as long as 71 days, when gro...

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Detalles Bibliográficos
Autores principales: Craciun, E. C., Oppenheimer, E. H.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1926
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131145/
https://www.ncbi.nlm.nih.gov/pubmed/19869163
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author Craciun, E. C.
Oppenheimer, E. H.
author_facet Craciun, E. C.
Oppenheimer, E. H.
author_sort Craciun, E. C.
collection PubMed
description The technique is described whereby vaccinia "granules" are separated from all other material of glycerolated vaccinia calf lymph and cultivated in vitro with embryonic tissues. These "granules"remain alive, as tested by rabbit corneal inoculation, for as long as 71 days, when grown in connection with growing tissue; they fail to remain potent if cultivated with dying cells, showing in this way the same characteristics as whole vaccine virus. The potency of the " granules" increases with the age of the culture under the first mentioned conditions. The fluid part of the vaccinia lymph which remains after the removal of all "granules," is impotent under all conditions.
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spelling pubmed-21311452008-04-18 THE CULTIVATION OF THE GRANULES OF VACCINIA VIRUS Craciun, E. C. Oppenheimer, E. H. J Exp Med Article The technique is described whereby vaccinia "granules" are separated from all other material of glycerolated vaccinia calf lymph and cultivated in vitro with embryonic tissues. These "granules"remain alive, as tested by rabbit corneal inoculation, for as long as 71 days, when grown in connection with growing tissue; they fail to remain potent if cultivated with dying cells, showing in this way the same characteristics as whole vaccine virus. The potency of the " granules" increases with the age of the culture under the first mentioned conditions. The fluid part of the vaccinia lymph which remains after the removal of all "granules," is impotent under all conditions. The Rockefeller University Press 1926-05-31 /pmc/articles/PMC2131145/ /pubmed/19869163 Text en Copyright © Copyright, 1926, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Craciun, E. C.
Oppenheimer, E. H.
THE CULTIVATION OF THE GRANULES OF VACCINIA VIRUS
title THE CULTIVATION OF THE GRANULES OF VACCINIA VIRUS
title_full THE CULTIVATION OF THE GRANULES OF VACCINIA VIRUS
title_fullStr THE CULTIVATION OF THE GRANULES OF VACCINIA VIRUS
title_full_unstemmed THE CULTIVATION OF THE GRANULES OF VACCINIA VIRUS
title_short THE CULTIVATION OF THE GRANULES OF VACCINIA VIRUS
title_sort cultivation of the granules of vaccinia virus
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131145/
https://www.ncbi.nlm.nih.gov/pubmed/19869163
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