FURTHER OBSERVATIONS ON THE INABILITY TO TRANSMIT A RABBIT NEOPLASM BY CELL-FREE MATERIALS

It has not been possible to propagate a malignant neoplasm of the rabbit with cell-free filtrates, or desiccated tumor tissue or by the use of fluid media kept in contact with tumor tissue. These findings confirm the results of previous experiments carried out with early generations of the tumor. Th...

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Detalles Bibliográficos
Autores principales: Pearce, Louise, Murphy, James B.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1927
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131167/
https://www.ncbi.nlm.nih.gov/pubmed/19869333
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author Pearce, Louise
Murphy, James B.
author_facet Pearce, Louise
Murphy, James B.
author_sort Pearce, Louise
collection PubMed
description It has not been possible to propagate a malignant neoplasm of the rabbit with cell-free filtrates, or desiccated tumor tissue or by the use of fluid media kept in contact with tumor tissue. These findings confirm the results of previous experiments carried out with early generations of the tumor. The existence of an agent distinct from the tumor cell which could initiate growth has not been demonstrated. The experiments bring out an essential biological difference between this mammalian neoplasm which is considered to be of epithelial origin and certain filtrable tumors of fowls which have been classified as sarcomata.
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spelling pubmed-21311672008-04-18 FURTHER OBSERVATIONS ON THE INABILITY TO TRANSMIT A RABBIT NEOPLASM BY CELL-FREE MATERIALS Pearce, Louise Murphy, James B. J Exp Med Article It has not been possible to propagate a malignant neoplasm of the rabbit with cell-free filtrates, or desiccated tumor tissue or by the use of fluid media kept in contact with tumor tissue. These findings confirm the results of previous experiments carried out with early generations of the tumor. The existence of an agent distinct from the tumor cell which could initiate growth has not been demonstrated. The experiments bring out an essential biological difference between this mammalian neoplasm which is considered to be of epithelial origin and certain filtrable tumors of fowls which have been classified as sarcomata. The Rockefeller University Press 1927-07-31 /pmc/articles/PMC2131167/ /pubmed/19869333 Text en Copyright © Copyright, 1927, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Pearce, Louise
Murphy, James B.
FURTHER OBSERVATIONS ON THE INABILITY TO TRANSMIT A RABBIT NEOPLASM BY CELL-FREE MATERIALS
title FURTHER OBSERVATIONS ON THE INABILITY TO TRANSMIT A RABBIT NEOPLASM BY CELL-FREE MATERIALS
title_full FURTHER OBSERVATIONS ON THE INABILITY TO TRANSMIT A RABBIT NEOPLASM BY CELL-FREE MATERIALS
title_fullStr FURTHER OBSERVATIONS ON THE INABILITY TO TRANSMIT A RABBIT NEOPLASM BY CELL-FREE MATERIALS
title_full_unstemmed FURTHER OBSERVATIONS ON THE INABILITY TO TRANSMIT A RABBIT NEOPLASM BY CELL-FREE MATERIALS
title_short FURTHER OBSERVATIONS ON THE INABILITY TO TRANSMIT A RABBIT NEOPLASM BY CELL-FREE MATERIALS
title_sort further observations on the inability to transmit a rabbit neoplasm by cell-free materials
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131167/
https://www.ncbi.nlm.nih.gov/pubmed/19869333
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