STUDIES ON THE OXIDATION AND REDUCTION OF IMMUNOLOGICAL SUBSTANCES : II. THE HEMOTOXIN OF THE WELCH BACILLUS.

A study has been made of the oxidation and reduction of the hemotoxin of the Welch bacillus. The oxidation of the lysin results in the loss of its hemolytic activity. The "inactive" oxidation product of the Welch lysin may be reversed to the "active" lysin by treatment with biolo...

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Detalles Bibliográficos
Autor principal: Neill, James M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1926
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131177/
https://www.ncbi.nlm.nih.gov/pubmed/19869181
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author Neill, James M.
author_facet Neill, James M.
author_sort Neill, James M.
collection PubMed
description A study has been made of the oxidation and reduction of the hemotoxin of the Welch bacillus. The oxidation of the lysin results in the loss of its hemolytic activity. The "inactive" oxidation product of the Welch lysin may be reversed to the "active" lysin by treatment with biological or chemical reducing agents. The lysin, both in its reduced and oxidized form, is irreversibly inactivated by the same heat treatment. The pH of the system is an important factor in the oxidation of the lysin, the process proceeding much more rapidly at a pH above 7.0.
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spelling pubmed-21311772008-04-18 STUDIES ON THE OXIDATION AND REDUCTION OF IMMUNOLOGICAL SUBSTANCES : II. THE HEMOTOXIN OF THE WELCH BACILLUS. Neill, James M. J Exp Med Article A study has been made of the oxidation and reduction of the hemotoxin of the Welch bacillus. The oxidation of the lysin results in the loss of its hemolytic activity. The "inactive" oxidation product of the Welch lysin may be reversed to the "active" lysin by treatment with biological or chemical reducing agents. The lysin, both in its reduced and oxidized form, is irreversibly inactivated by the same heat treatment. The pH of the system is an important factor in the oxidation of the lysin, the process proceeding much more rapidly at a pH above 7.0. The Rockefeller University Press 1926-07-31 /pmc/articles/PMC2131177/ /pubmed/19869181 Text en Copyright © Copyright, 1926, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Neill, James M.
STUDIES ON THE OXIDATION AND REDUCTION OF IMMUNOLOGICAL SUBSTANCES : II. THE HEMOTOXIN OF THE WELCH BACILLUS.
title STUDIES ON THE OXIDATION AND REDUCTION OF IMMUNOLOGICAL SUBSTANCES : II. THE HEMOTOXIN OF THE WELCH BACILLUS.
title_full STUDIES ON THE OXIDATION AND REDUCTION OF IMMUNOLOGICAL SUBSTANCES : II. THE HEMOTOXIN OF THE WELCH BACILLUS.
title_fullStr STUDIES ON THE OXIDATION AND REDUCTION OF IMMUNOLOGICAL SUBSTANCES : II. THE HEMOTOXIN OF THE WELCH BACILLUS.
title_full_unstemmed STUDIES ON THE OXIDATION AND REDUCTION OF IMMUNOLOGICAL SUBSTANCES : II. THE HEMOTOXIN OF THE WELCH BACILLUS.
title_short STUDIES ON THE OXIDATION AND REDUCTION OF IMMUNOLOGICAL SUBSTANCES : II. THE HEMOTOXIN OF THE WELCH BACILLUS.
title_sort studies on the oxidation and reduction of immunological substances : ii. the hemotoxin of the welch bacillus.
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131177/
https://www.ncbi.nlm.nih.gov/pubmed/19869181
work_keys_str_mv AT neilljamesm studiesontheoxidationandreductionofimmunologicalsubstancesiithehemotoxinofthewelchbacillus

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