STUDIES ON COMPLEMENT FIXATION IN TUBERCULOSIS. III

The prolonged extraction of the tubercle bacillus with boiling ethyl alcohol, followed by one or more reprecipitations by chilling the hot alcoholic solution, easily yields a preparation very active as antigen in the complement fixation reaction. This preparation gives a precipitation reaction with...

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Detalles Bibliográficos
Autor principal: Lewis, Paul A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1927
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131207/
https://www.ncbi.nlm.nih.gov/pubmed/19869283
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author Lewis, Paul A.
author_facet Lewis, Paul A.
author_sort Lewis, Paul A.
collection PubMed
description The prolonged extraction of the tubercle bacillus with boiling ethyl alcohol, followed by one or more reprecipitations by chilling the hot alcoholic solution, easily yields a preparation very active as antigen in the complement fixation reaction. This preparation gives a precipitation reaction with high dilution of the normal blood serum of a number of species. The precipitation reaction presents as a peculiar feature a very long pro-zone and is further dependent on a preceding heat treatment of the serum for its demonstration. Occurring as a reaction of normal serum, the reaction is apparently not influenced by immunization sufficient to develop moderate specific complement fixation reactions.
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spelling pubmed-21312072008-04-18 STUDIES ON COMPLEMENT FIXATION IN TUBERCULOSIS. III Lewis, Paul A. J Exp Med Article The prolonged extraction of the tubercle bacillus with boiling ethyl alcohol, followed by one or more reprecipitations by chilling the hot alcoholic solution, easily yields a preparation very active as antigen in the complement fixation reaction. This preparation gives a precipitation reaction with high dilution of the normal blood serum of a number of species. The precipitation reaction presents as a peculiar feature a very long pro-zone and is further dependent on a preceding heat treatment of the serum for its demonstration. Occurring as a reaction of normal serum, the reaction is apparently not influenced by immunization sufficient to develop moderate specific complement fixation reactions. The Rockefeller University Press 1927-03-31 /pmc/articles/PMC2131207/ /pubmed/19869283 Text en Copyright © Copyright, 1927, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Lewis, Paul A.
STUDIES ON COMPLEMENT FIXATION IN TUBERCULOSIS. III
title STUDIES ON COMPLEMENT FIXATION IN TUBERCULOSIS. III
title_full STUDIES ON COMPLEMENT FIXATION IN TUBERCULOSIS. III
title_fullStr STUDIES ON COMPLEMENT FIXATION IN TUBERCULOSIS. III
title_full_unstemmed STUDIES ON COMPLEMENT FIXATION IN TUBERCULOSIS. III
title_short STUDIES ON COMPLEMENT FIXATION IN TUBERCULOSIS. III
title_sort studies on complement fixation in tuberculosis. iii
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131207/
https://www.ncbi.nlm.nih.gov/pubmed/19869283
work_keys_str_mv AT lewispaula studiesoncomplementfixationintuberculosisiii

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