THE INFLUENCE OF THYROIDECTOMY, SPLENECTOMY, GONADECTOMY, AND SUPRARENALECTOMY UPON THE DEVELOPMENT OF EXPERIMENTAL ATHEROSCLEROSIS IN RABBITS

Alimentary hypercholesterolemia acting over a sufficient period of time (in rabbits with all organs intact, 110 days or longer) causes deposition of cholesterol within the intima of the aorta. Deposition of cholesterol within the intima of the aorta initiates the formation of experimental atheromata...

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Detalles Bibliográficos
Autor principal: Shapiro, Shepard
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1927
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131217/
https://www.ncbi.nlm.nih.gov/pubmed/19869275
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author Shapiro, Shepard
author_facet Shapiro, Shepard
author_sort Shapiro, Shepard
collection PubMed
description Alimentary hypercholesterolemia acting over a sufficient period of time (in rabbits with all organs intact, 110 days or longer) causes deposition of cholesterol within the intima of the aorta. Deposition of cholesterol within the intima of the aorta initiates the formation of experimental atheromata. Thyroidectomy, splenectomy, and gonadectomy augment hypercholesterolemia and thereby facilitate and accelerate the development of experimental atheromata of the aorta in rabbits. Sublethal suprarenal insufficiency does not increase the susceptibility of rabbits to the development of such atheromata.
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spelling pubmed-21312172008-04-18 THE INFLUENCE OF THYROIDECTOMY, SPLENECTOMY, GONADECTOMY, AND SUPRARENALECTOMY UPON THE DEVELOPMENT OF EXPERIMENTAL ATHEROSCLEROSIS IN RABBITS Shapiro, Shepard J Exp Med Article Alimentary hypercholesterolemia acting over a sufficient period of time (in rabbits with all organs intact, 110 days or longer) causes deposition of cholesterol within the intima of the aorta. Deposition of cholesterol within the intima of the aorta initiates the formation of experimental atheromata. Thyroidectomy, splenectomy, and gonadectomy augment hypercholesterolemia and thereby facilitate and accelerate the development of experimental atheromata of the aorta in rabbits. Sublethal suprarenal insufficiency does not increase the susceptibility of rabbits to the development of such atheromata. The Rockefeller University Press 1927-03-31 /pmc/articles/PMC2131217/ /pubmed/19869275 Text en Copyright © Copyright, 1927, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Shapiro, Shepard
THE INFLUENCE OF THYROIDECTOMY, SPLENECTOMY, GONADECTOMY, AND SUPRARENALECTOMY UPON THE DEVELOPMENT OF EXPERIMENTAL ATHEROSCLEROSIS IN RABBITS
title THE INFLUENCE OF THYROIDECTOMY, SPLENECTOMY, GONADECTOMY, AND SUPRARENALECTOMY UPON THE DEVELOPMENT OF EXPERIMENTAL ATHEROSCLEROSIS IN RABBITS
title_full THE INFLUENCE OF THYROIDECTOMY, SPLENECTOMY, GONADECTOMY, AND SUPRARENALECTOMY UPON THE DEVELOPMENT OF EXPERIMENTAL ATHEROSCLEROSIS IN RABBITS
title_fullStr THE INFLUENCE OF THYROIDECTOMY, SPLENECTOMY, GONADECTOMY, AND SUPRARENALECTOMY UPON THE DEVELOPMENT OF EXPERIMENTAL ATHEROSCLEROSIS IN RABBITS
title_full_unstemmed THE INFLUENCE OF THYROIDECTOMY, SPLENECTOMY, GONADECTOMY, AND SUPRARENALECTOMY UPON THE DEVELOPMENT OF EXPERIMENTAL ATHEROSCLEROSIS IN RABBITS
title_short THE INFLUENCE OF THYROIDECTOMY, SPLENECTOMY, GONADECTOMY, AND SUPRARENALECTOMY UPON THE DEVELOPMENT OF EXPERIMENTAL ATHEROSCLEROSIS IN RABBITS
title_sort influence of thyroidectomy, splenectomy, gonadectomy, and suprarenalectomy upon the development of experimental atherosclerosis in rabbits
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131217/
https://www.ncbi.nlm.nih.gov/pubmed/19869275
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AT shapiroshepard influenceofthyroidectomysplenectomygonadectomyandsuprarenalectomyuponthedevelopmentofexperimentalatherosclerosisinrabbits

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